Molecular structures of nonvolatile components in the Haihong fruit wine and their free radical scavenging effect. (15th August 2021)

• Record Type: Journal Article
• Authors: Hui, Yang; Wen, Su; Lihong, Wang; Chuang, Wang; Chaoyun, Wang
• Is Part Of: Food chemistry. Volume 353(2021)
• Publication Date: 2021-08-15
• Subjects: Haihong fruit wine -- Nonvolatile components -- Conjugation effect -- Free radical -- Anti-oxidation -- Chemical shift; Hyperoside, (PubChem CID: 5281643) -- Rutin, (PubChem CID: 5280805) -- Catechin, (PubChem CID: 9064) -- Epicatechin, (PubChem CID: 72276) -- Ursolic acid, (PubChem CID: 64945) -- β-sitosterol, (PubChem CID: 222284) -- Naringin dihydrochalcone, (PubChem CID:9894584) -- Caffeic acid, (PubChem CID: 689043) -- Oleanolic acid, (PubChem CID: 10494) -- Chlorogenic acid, (PubChem CID: 1794427) -- Gentianic acid, (PubChem CID: 5281636) -- Gallic acid, (PubChem CID: 370) -- Vanillic acid, (PubChem CID: 8468); Food -- Analysis -- Periodicals; Food -- Composition -- Periodicals; 664
• DOI: 10.1016/j.foodchem.2021.129298
• Languages: English
• ISSNs: 0308-8146

Abstract

Highlights: The radical scavenging effect of flavonoids is closely related to the structure of diphenol. The electron conjugation in reactant is a key factor for free radical scavenging. The chemical shift of phenol hydrogen is a measure of radical scavenging ability. Haihong fruit wine can enhance the activities of SOD, CAT and GPX in mice liver. Abstract: In order to investigate the correlation between free radical scavenging effect and the related molecular structures of active substances in the Haihong fruit ( Malus Micromalus Makino ) wine, sixteen kinds of components were isolated from the fruit wine. The structures of thirteen components were identified by UV, FTIR, LC-MS, 1D-NMR and 2D-NMR. The scavenging abilities of the fruit wine on DPPH (2, 2-Diphenyl-1 -picrylhydrazyl radical), OH, O2 − and the protective effects on red blood cell, SOD (Superoxide Dismutase), CAT(Catalase) and GPX(glutathione peroxidases) in aging mice tissues were studied. Results showed that the structures of o -diphenol and m -diphenol play an important role in scavenging free radicals. A larger conjugation system in functional molecule is conducive to getting a higher scavenging rate of free radicals. When the chemical shift of phenol hydrogen is lower, the anti-oxygenation ability is stronger. The fruit wine exhibits a strong scavenging ability on free radicals. It can inhibit the damage of red blood cells caused by OH radical.