Antioxidant and immunoregulatory activity of polysaccharides from adzuki beans (Vigna angularis). (November 2015)

• Record Type: Journal Article
• Authors: Yao, Yang; Xue, Peng; Zhu, Yingying; Gao, Yue; Ren, Guixing
• Is Part Of: Food research international. Volume 77:Part 2(2015:Nov.)
• Page Start: 251
• Page End: 256
• Publication Date: 2015-11
• Subjects: Adzuki beans -- Water-extractable polysaccharide -- Alkali-extractable polysaccharide; Food -- Analysis -- Periodicals; Food industry and trade -- Periodicals; Food industry and trade -- Canada -- Periodicals; Food Technology -- Periodicals; Food -- Periodicals; Food-Processing Industry -- Periodicals; Aliments -- Industrie et commerce -- Périodiques; Aliments -- Industrie et commerce -- Canada -- Périodiques; Aliments -- Recherche -- Périodiques; Food industry and trade; Canada; Periodicals; Electronic journals; 664.005
• DOI: 10.1016/j.foodres.2015.05.029
• Languages: English
• ISSNs: 0963-9969

Abstract

Abstract: Water-extractable and alkali-extractable polysaccharides from the seed of adzuki beans and their three polysaccharide sub-fractions were isolated and purified by anion-exchange and gel filtration chromatography. AWP-1 and AWP-2 were composed of Rha, Ara, Man, Gal and Glu. AAP-1 was composed of Rha, Ara, Man, Gal and GalA. The antioxidant and immunoregulatory activities of the polysaccharides were evaluated. The results indicated that AWP-1, AWP-2, and AAP-1 had significant antioxidant and immunoregulatory activities. The results suggest that AWP-1, AWP-2, and AAP-1 have therapeutic implications in the treatment of inflammation and inflammatory-related disease. Highlights: Three polysaccharide sub-fractions were isolated and purified from adzuki beans. Their structural features were analyzed using FT-IR and HPSEC-MALLS-RID. The polysaccharide sub-fractions have antioxidant and immunoregulatory activities.