Phytochemical and biological investigations on the pollen from industrial hemp male inflorescences. (November 2022)

• Record Type: Journal Article
• Authors: Acquaviva, Alessandra; Cristina Di Simone, Simonetta; Canini, Antonella; Braglia, Roberto; Di Marco, Gabriele; Campana, Claudia; Angelini, Paola; Angeles Flores, Giancarlo; Venanzoni, Roberto; Loreta Libero, Maria; Tirillini, Bruno; Zengin, Gokhan; Chiavaroli, Annalisa; Recinella, Lucia; Leone, Sheila; Nilofar, ; Brunetti, Luigi; Orlando, Giustino; Menghini, Luigi; Ferrante, Claudio
• Is Part Of: Food research international. Volume 161(2022)
• Publication Date: 2022-11
• Subjects: Industrial hemp -- Male inflorescences -- Pollen -- Palynological analysis -- Phenolic compounds -- Antimicrobial effects; Food -- Analysis -- Periodicals; Food industry and trade -- Periodicals; Food industry and trade -- Canada -- Periodicals; Food Technology -- Periodicals; Food -- Periodicals; Food-Processing Industry -- Periodicals; Aliments -- Industrie et commerce -- Périodiques; Aliments -- Industrie et commerce -- Canada -- Périodiques; Aliments -- Recherche -- Périodiques; Food industry and trade; Canada; Periodicals; Electronic journals; 664.005
• DOI: 10.1016/j.foodres.2022.111883
• Languages: English
• ISSNs: 0963-9969

Abstract

Graphical abstract: Highlights: Polyphenolic composition of hydroalcoholic and water extracts from hemp pollen. Antioxidant effects induced by hydroalcoholic and water extracts from hemp pollen. Antimicrobial effects induced by hydroalcoholic and water extracts from hemp pollen. Abstract: Cannabis sativa L. belongs to the Cannabaceae family and includes annual, robust, fast-growing and generally dioecious plants. Industrial hemp, and particularly the inflorescences, has been recently recognized as important source of bioactive extracts with antioxidant and antimicrobial effects. The goal of the present study was to explore botanical, phytochemical, and biological properties of water and hydroalcoholic hemp pollen extracts from male inflorescences. The extracts from hemp pollen were found rich in phenolic compounds, such as hydroxytyrosol, coumaric acid, and hesperitin. The phenolic profile was also consistent with the observed scavenging/reducing, enzyme inhibitory, and antimicrobial properties of the extracts. Regarding the antimicrobial effects, Escherichia coli, Trycophyton rubrum, and T. tonsurans were the most sensitive to growth inhibitory effects (MIC values: 9.92–79.37 µg/mL) of the extracts. Whereas, null effects on prostate PC3 and myocyte C2C12 cell viability, in the range 1–1000 µg/mL, are consistent with MIC values and suggest extracts' biocompatibility. The experimental data obtained, which are not reflected in the literature as the topic of hemp pollen is almost completely unexplored, confirm the innovativeness of a product obtained directly from bees, which in the face of greater variability and complexity can reserve promising applications in food, pharmaceutical, and cosmetic sectors.