Genetic diversity, antimicrobial, nutritional, and phytochemical properties of Chenopodium album: A comprehensive review. (April 2022)

• Record Type: Journal Article
• Authors: Chamkhi, Imane; Charfi, Saoulajan; El Hachlafi, Naoufal; Mechchate, Hamza; Guaouguaou, Fatima-Ezzahrae; El Omari, Nasreddine; Bakrim, Saad; Balahbib, Abdelaali; Zengin, Gokhan; Bouyahya, Abdelhakim
• Is Part Of: Food research international. Volume 154(2022)
• Publication Date: 2022-04
• Subjects: Chenopodium album -- Nutirional value -- Bioactive molecules -- Antimicriobial effects; Eos Essential Oils -- GC-MS Gas Chromatography-Mass Spectrometry -- MIC Minimal Inhibitory Concentration -- MBC Minimal Bactericidal Concentration -- GOX Graphene Oxide -- RGOX Reduces Graphene Oxide -- DPPH 2, 2-Diphenyl-1-Picryl-hydrazyl-Hydrate -- ABTS 2, 2 -Azino-Bis(3-ethylbenzothiazoline-6-Sulfonic -- FRAP Ferric Reducing Antioxidant Power -- NO Nitric Oxide -- TOS Total Oxidant Status -- TAS Total Antioxidant Status -- AST Aspartate Aminotransferase -- ALT Alanine Aminotransferase -- ALP Phosphatase Alcaline -- SOD Superoxide Dismutase -- ROS Reactive Oxygen Species -- LDL Low Density Lipoprotein -- LDH Lactate Deshydrogenase; Food -- Analysis -- Periodicals; Food industry and trade -- Periodicals; Food industry and trade -- Canada -- Periodicals; Food Technology -- Periodicals; Food -- Periodicals; Food-Processing Industry -- Periodicals; Aliments -- Industrie et commerce -- Périodiques; Aliments -- Industrie et commerce -- Canada -- Périodiques; Aliments -- Recherche -- Périodiques; Food industry and trade; Canada; Periodicals; Electronic journals; 664.005
• DOI: 10.1016/j.foodres.2022.110979
• Languages: English
• ISSNs: 0963-9969

Abstract

Graphical abstract: Highlights: The traditional use of Chenopodium album was reported. The nutraceutical properties of Chenopodium album were reviewed with earlier papers from different databases. Chemical bioactive compounds of Chenopodium album such as phenolic acids, terpenoids, and flavonoids were observed. This review will be a scientific starting point for further studies regarding Chenopodium album. Abstract: Chenopodium album L., is a medicinal plant widely cultivated in Europe, North America, Iran, South Africa, Australia, South America, and Asia. This species is commonly used in folk medicine to treat many diseases such as cancer, viral infections, parasitic diseases, gastrointestinal disorders, as well as bacterial and fungal infections. The present review was carried out to highlight previous studies on C. album, including its botanical description, geographical distribution, genetic diversity, ecological variability, ethnomedicinal use, bioactive compounds, pharmacological properties, and toxicology. The data collected on C. album was generated using various scientific research databases such as SciFinder, PubMed, Google Scholar, SpringerLink, ScienceDirect, Web of Science, Scopus, and Wiley Online. In this review, the data presented focus on C. album to elucidate its ethnomedicinal use, pharmacological activities, and chemical composition in order to investigate the possible therapeutic pathways of the plant. Analysis of the findings showed that C. album has a capital power in various therapeutic uses such as antibacterial, antifungal, antiviral, antiparasitic, antipruritic, anticancer, antiulcer, antirheumatic, antidiabetic, antihyperlipidemic, antioxidant, and anti-inflammatory as well as other biological functions. Indeed, data on the chemical composition of the extracts and essential oils of this plant revealed its richness in secondary metabolites. The results of this paper prove that the pharmacological properties of C. album confirm its traditional importance in the international traditional pharmacopeia. This species notably exhibits various biological activities; antibacterial, antifungal, and antioxidant effects. However, toxicological investigations and pharmacokinetic validation are necessary in order to identify a possible toxicity of this plant for future clinical trials and to validate its bioavailability.