Dietary strategies with anti-aging potential: Dietary patterns and supplements. (August 2022)

• Record Type: Journal Article
• Authors: Duan, Hui; Pan, Jiani; Guo, Min; Li, Jinwei; Yu, Leilei; Fan, Liuping
• Is Part Of: Food research international. Volume 158(2022)
• Publication Date: 2022-08
• Subjects: Dietary patterns -- Dietary supplements -- Gut microbiota -- Probiotics -- Aging; ADF alternate-day fasting -- CCL2 a kind of chemokines -- CoQ10 Coenzyme Q10 -- CR caloric restriction -- CRMs CR mimetics -- DASH Dietary approaches to stop hypertension -- ESH ergothionine -- FMD fasting-mimicking diet -- IF intermittent fasting -- Keto diet Ketogenic diet -- LPS Lipopolysaccharide -- LBP LBS-binding proten -- MCT1 monocarboxylate transporter-1 -- MedDiet Mediterranean diet -- NMN nicotinamide mononucleotide -- NR nicotinamide riboside -- NFκB nuclear factor kappa B -- NAM nicotinamide -- PCC1 procyanidin C1 -- PPAR peroxisome proliferator activated receptor -- PQQ pyrroloquinoline quinone -- SASP senescence-associated secretory phenotype -- SCFAs short-chain fatty acids -- SNPs single nucleotide polymorphisms -- TLR Toll-like receptor -- TRE time-restricted diet -- UPF ultra-processed food -- V/M vitamins and essential minerals/elements; Food -- Analysis -- Periodicals; Food industry and trade -- Periodicals; Food industry and trade -- Canada -- Periodicals; Food Technology -- Periodicals; Food -- Periodicals; Food-Processing Industry -- Periodicals; Aliments -- Industrie et commerce -- Périodiques; Aliments -- Industrie et commerce -- Canada -- Périodiques; Aliments -- Recherche -- Périodiques; Food industry and trade; Canada; Periodicals; Electronic journals; 664.005
• DOI: 10.1016/j.foodres.2022.111501
• Languages: English
• ISSNs: 0963-9969

Abstract

Graphical abstract: Highlights: Okinawan, Medit, DASH diets, CR and IF are reliable dietary patterns for anti-aging. Ketogenic diet is a controversial dietary pattern for anti-aging. Combined use of dietary patterns and supplements can achieve additive effects. Nutrigenomics plays a vital role in personalized dietary strategy. Identifying accurate aging biomarkers is crucial to precise dietary intervention. Abstract: Dietary intervention is a safe, broad-spectrum, and low-cost preventive strategy for slow aging. The Okinawan, Mediterranean, and Dietary approaches to stop hypertension (DASH) diets, as well as caloric restriction (CR) and intermittent fasting (IF), are classic and reliable dietary patterns that slow aging by regulating nutrient-sensing pathways, gut microbiota, metabolism, and immunity. Moreover, the proportion of the three macronutrients (carbohydrate, protein and fat) is also vital for slowing aging, but the debates about the appropriate proportion, especially the ratio of carbohydrates and proteins, remain unknown. Strict and lifelong adherence to these regimens is difficult, thereby promoting the emergence of various dietary supplements, including natural CR mimics, probiotics, natural senolytics, vitamins and essential minerals. Combinations of different dietary patterns and supplements with distinct pathways may have additive effects. Individuals' aging speed and dietary response are highly variable, thus highlighting the need for precise anti-aging dietary intervention. Nutrigenomics plays an important role in personalized dietary strategies. Therefore, this review critically compares the anti-aging effects of various dietary patterns and supplements, analyzes their mechanisms and combined use, and proposes future research directions to achieve personalized dietary strategies for slowing aging.