Black chokeberry (Aronia melanocarpa) extracts in terms of geroprotector criteria. (August 2021)

• Record Type: Journal Article
• Authors: Platonova, Elena Y.; Shaposhnikov, Mikhail V.; Lee, Hye-Yeon; Lee, Ji-Hyeon; Min, Kyung-Jin; Moskalev, Alexey
• Is Part Of: Trends in food science & technology. Volume 114(2021)
• Page Start: 570
• Page End: 584
• Publication Date: 2021-08
• Subjects: Aronia melanocarpa -- Extract -- Geroprotector -- Lifespan -- Polyphenolic compounds -- Anthocyanins -- Berry extract; Food industry and trade -- Periodicals; Food -- Biotechnology -- Periodicals; 664.005
• DOI: 10.1016/j.tifs.2021.06.020
• Languages: English
• ISSNs: 0924-2244

Abstract

Abstract: Background: Black chokeberry ( Aronia melanocarpa (Micht.) Elliot) is a great dietary source of a wide range of biologically active compounds, such as anthocyanins, flavonoids, other phenolic compounds, vitamins, and minerals that have a wide range of health benefits. Scope and approach: Here we provide an overview of the in vitro and in vivo effects of A. melanocarpa extracts to reveal its potential anti-aging properties in terms of meeting the criteria for a geroprotector. The possible mechanisms of the anti-aging action of black chokeberry extracts are highlighted. Key findings and conclusions: A. melanocarpa extract exhibit geroprotective activity like lifespan extension, anti-proliferative activity, improvement of glucose and lipid metabolism, amelioration of neurodegenerative disorders, antiviral and antibacterial activity, protection of the gastrointestinal system. The mechanisms of A. melanocarpa anti-aging action may be associated with the hormesis effect, activation of antioxidant-defense, modulation of insulin/IGF-1 signaling, and anti-inflammatory activity. Highlights: A. melanocarpa is a rich source of polyphenols with versatile health benefits. Aronia has geroprotective potential due to the hormetic effect of phytochemicals. The anti-aging effect is linked with activation of stress response mechanisms. Potential adverse effects of polyphenols should be taken into account.