A mango (Mangifera indica L.) juice by-product reduces gastrointestinal and upper respiratory tract infection symptoms in children. (October 2020)

• Record Type: Journal Article
• Authors: Anaya-Loyola, Miriam A.; García-Marín, Gabriela; García-Gutiérrez, David G.; Castaño-Tostado, Eduardo; Reynoso-Camacho, Rosalía; López-Ramos, Juan E.; Enciso-Moreno, José A.; Pérez-Ramírez, Iza F.
• Is Part Of: Food research international. Volume 136(2020)
• Publication Date: 2020-10
• Subjects: Mango -- By-product -- Bagasse -- Upper respiratory -- Gastrointestinal -- Immune system -- Polyphenols -- Dietary fiber; JBP juice by-product -- DF dietary fiber -- SDF soluble dietary fiber -- IDF insoluble dietary fiber -- SCFA short-chain fatty acids -- EPP extractable polyphenols -- HPP hydrolysable polyphenols -- UPLC ultra-performance liquid chromatography -- QTOF quadrupole/time-of-flight -- MS mass spectrometry -- ESI electrospray ionization -- Ig immunoglobulin -- IL interleukin -- MIF macrophage migration inhibitory factor -- MIP macrophage inflammatory protein -- OPN osteopontin -- PAI plasminogen activator inhibitor -- PF platelet factor -- uPAR urokinase-type plasminogen activator receptor; Food -- Analysis -- Periodicals; Food industry and trade -- Periodicals; Food industry and trade -- Canada -- Periodicals; Food Technology -- Periodicals; Food -- Periodicals; Food-Processing Industry -- Periodicals; Aliments -- Industrie et commerce -- Périodiques; Aliments -- Industrie et commerce -- Canada -- Périodiques; Aliments -- Recherche -- Périodiques; Food industry and trade; Canada; Periodicals; Electronic journals; 664.005
• DOI: 10.1016/j.foodres.2020.109492
• Languages: English
• ISSNs: 0963-9969

Abstract

Graphical abstract: Highlights: Mango juice by-product (JBP) modulated proteins of the immune system in children. Mango JBP reduced gastrointestinal and respiratory infection symptoms in children. Mango JBP is rich in extractable and non-extractable polyphenols. Abstract: The study aimed to evaluate the effect of a mango juice by-product (JBP) on upper-respiratory and gastrointestinal tract infection symptoms in children (6–8 y) in a randomized, double-blind, parallel, case-control study. For two months, children drank either flavored water (control group) or a mango JBP-based beverage (0.04 g·ml −1 ; treatment group); such beverage provided 1.1 g, 278.6 mg and 7.8 mg of dietary fiber, extractable polyphenols (mono-to-hepta galloyl hexosides, mangiferin), and hydrolysable polyphenols (ellagic/gallic acid) per portion, respectively. Mango JBP reduced the incidence of gastrointestinal (flatulencies and abdominal inflammation; p ≤ 0.007) and upper-tract respiratory (crystalline mucus, itchy throat, runny nose, itchy nose, and sneezing; p ≤ 0.038) and such benefits were associated to increased serum levels of PAI-I, MIP-1a, and MIP-1b (p ≤ 0.04) and decreased levels of IgG, MIF, and osteopontin (p ≤ 0.01). We concluded that JBP-based beverage has immunomodulatory properties, useful to prevent or even treat common infectious diseases in school-age children.