A next generation probiotic, Akkermansia muciniphila. Issue 19 (28th October 2019)

• Record Type: Journal Article
• Authors: Zhai, Qixiao; Feng, Saisai; Arjan, Narbad; Chen, Wei
• Is Part Of: Critical reviews in food science and nutrition. Volume 59:Issue 19(2019)
• Page Start: 3227
• Page End: 3236
• Publication Date: 2019-10-28
• Subjects: Akkermansia muciniphila -- mucin -- diet -- host health and disease; Food industry and trade -- Periodicals; Nutrition -- Periodicals; Nutrition -- Periodicals; Food -- Periodicals; Diet -- Periodicals; Review Literature -- Periodicals; Nutrition; Food; Diet; Review Literature; 664
• DOI: 10.1080/10408398.2018.1517725
• Languages: English
• ISSNs: 1040-8398

Abstract

Abstract: Akkermansia muciniphila, a symbiotic bacterium of the mucus layer, can utilize mucin as its sole carbon, nitrogen, and energy source. As an abundant resident in the intestinal tract of humans and animals, the probiotic effects of A. muciniphila including metabolic modulation, immune regulation and gut health protection, have been widely investigated. Various diseases such as metabolic syndromes and auto-immnue diseases have been reported to be associated with the disturbance of the abundance of A. muciniphila . In this review, we describe the biological characterization of A. muciniphia, the factors that influence its colonization of the intestinal tract; and discuss the current state of our knowledge on its role in host health and disease.