Chemical characterization and protective effect of the Bactris setosa Mart. fruit against oxidative/nitrosative stress. (1st April 2017)

• Record Type: Journal Article
• Authors: Boeing, Joana Schuelter; Ribeiro, Daniela; Chisté, Renan Campos; Visentainer, Jesuí Vergílio; Costa, Vera Marisa; Freitas, Marisa; Fernandes, Eduarda
• Is Part Of: Food chemistry. Volume 220(2017)
• Page Start: 427
• Page End: 437
• Publication Date: 2017-04-01
• Subjects: (−)-Epicatechin (PubChem CID: 72276) -- (+)-Catechin (PubChem CID: 9064) -- trans-Piceatannol (PubChem CID: 667639) -- Rutin (PubChem CID: 5280805) -- Cyanidin chloride (PubChem CID: 68247); Bactris setosa Mart. fruits -- Phenolic compounds -- Carotenoids -- ROS and RNS -- Neutrophils -- Caco-2 cells; Food -- Analysis -- Periodicals; Food -- Composition -- Periodicals; 664
• DOI: 10.1016/j.foodchem.2016.09.188
• Languages: English
• ISSNs: 0308-8146

Abstract

Highlights: Bioactive compounds of B. setosa fruit extracts are reported for the first time. B. setosa fruit extracts strongly scavenged physiologically relevant ROS and RNS. B. setosa fruit extracts have a modulator effect of neutrophils' oxidative burst. B. setosa fruit extracts protect Caco-2 cells against the toxicity caused by t -BHP. Peel extracts were shown to have the strongest activities measured. Abstract: Bactris setosa Mart. is a Brazilian tree from the palm family (Arecaceae), whose fruits are scientifically underexploited. Here, we report, for the first time, the identification and quantification of phenolic compounds and carotenoids in the pulp, seed, and peel extracts of B. setosa fruits and their in vitro biological activity. The anthocyanins cyanidin deoxyhexose hexoside and cyanidin hexoside and other phenolic compounds were detected mainly in the peel but also in the pulp extracts. All- trans -lutein was the unique carotenoid identified and quantified, and only in the peel extract. All extracts were able to scavenge reactive oxygen and nitrogen species (ROS and RNS, respectively), to modulate human neutrophils' oxidative burst and to protect Caco-2 cells against oxidative damage, the peel extract being the most efficient. This study indicates that extracts from B. setosa fruits, especially the peel extract, are a source of bioactive compounds with promising antioxidant and anti-inflammatory properties.