Cholesterol : Chemistry, Biochemistry, and Pathology /: Chemistry, Biochemistry, and Pathology. ([2015])

• Record Type: Book
• Further Information: Note: Edited by Robert P. Cook.
• Editors: Cook, Robert P
• Contents: Preface; ; List Of Contributors; ; 1. Historical Introduction; ; I. The Discovery and Occurrence of Cholesterol; ; II. Early Chemistry; ; III. Related Compounds; ; IV. Analytical Methods; ; V. Metabolism; ; References; ; 2. Chemistry; ; I. Introduction; ; II. Nomenclature; ; III. Table of Natural Sterols; ; IV. Occurrence and Large-Scale Isolation of Cholesterol; ; V. The Structure of Cholesterol; ; VI. Reactions of Cholesterol; ; VII. Physico-Chemical Measurements on Steroids; ; VIII. Digitonide Formation; ; IX. Color Reactions of Steroids; ; X. Tables of Physical Constants of Cholesterol Derivatives; ; References; ; 3. Methods of Isolation and Estimation of Sterols; ; I. Introduction; ; II. Isolation Procedures; ; III. Quantitative Determination of Sterols; ; IV. Physical Methods; ; V. Sterols in Parts of the Cell and in Plants; ; VI. Summary and Conclusions; ; References; ; 4. Distribution of Sterols in Organisms and in Tissues; ; I. Introduction; ; II. Whole Organisms; ; III. Distribution in Animal Tissues; ; IV. Sterols in Plants; ; V. The Sterol Content of Foodstuffs; ; VI. Conclusions; ; References; ; 5. The Physiology of the Circulating Cholesterol and Lipoproteins; ; I. The Distribution of Cholesterol between the Formed Elements of the Blood and the Blood Plasma; ; II. The Physical State of the Plasma Cholesterol; ; III. Species Differences; ; IV. Race; ; V. The Effect of Diet; ; VI. Plasma Cholesterol in Man; ; VII. Conclusions; ; References; ; 6. Biosynthesis of Cholesterol; ; I. Introduction; ; II. Pathways in Cholesterol Biosynthesis; ; III. Sites of Sterol Biosynthesis in Animal Tissues; ; IV. Sterol Biosynthesis in Yeast and Other Organisms; ; V. The Labeling of Sterols; ; References; ; 7. The Metabolism of Cholesterol and Other Sterols in the Animal Organism; ; I. Introduction; ; II. Absorption of Sterols from the Intestine (R.P.C.); ; III. Esterification of Cholesterol (R.G.G.); ; IV. Cholesterol Metabolism in the Liver (R.G.G.); ; V. Metabolism of Cholesterol in Extrahepatic Tissues ( R.G.G.); ; VI. Factors Influencing Cholesterol Biosynthesis, Turnover, and Distribution in Tissues (R.G.G.); ; VII. The Excretory Pathways (R.P.C.); ; VIII. The Metabolism of Other Sterols (R.P.C.); ; IX. Summary; ; References; ; 8. Conversion of Cholesterol to Steroid Hormones; ; I. Introduction; ; II. Historical Reflections; ; III. Corticoids; ; IV. Androgens; ; V. Estrogens; ; VI. The Problem of Alternative Pathways Involved in Steroid Hormone Biosynthesis; ; VII. Concluding Remarks; ; References; ; 9. Microscopical Localization of Cholesterol in Cells and Tissues; ; I. Introduction; ; II. Histological Demonstration of Cholesterol; ; III. Distribution of Cholesterol in Cells, Organs and Tissues; ; IV. Some Suggested Structural Functions of Cholesterol; ; References; ; 10. Pathological Manifestations of Abnormal Cholesterol Metabolism; ; I. Introduction; ; II. Normal Cholesterol Levels in Serum; ; III. Hypercholesteremia; ; IV. Hypocholesteremia; ; V. Diseases Characterized by Cholesterol Deposition; ; VI. Cholesterol and Cancer; ; Summary; ; References; ; 11. Treatment of Disorders of Cholesterol Metabolism; ; I. Diet; ; II. ß-Sitosterol; ; III. Nicotinic Acid; ; IV. Exercise; ; V. Reduction of Abnormal Arterial Pressure Levels; ; VI. Endocrine Therapy; ; VII. Anti-biosynthetic Compounds; ; VIII. Primary Hyperlipemias; ; IX. Secondary Hyperlipemias; ; References; ; 12. Evolutionary Aspects of the Sterols; ; I. Introduction; ; II. Sterols of Animals; ; III. Conclusions; ; References; ; 13. The Sterol Requirements of Insects and of Protozoa; ; I. Insects; ; II. Protozoa; ; References; ; 14. The Microbial Metabolism of Steroids; ; I. Introduction; ; II. Oxidation of Nuclear Positions in the Steroid Molecule; ; III. Degradation of Steroids; ; IV. Biosynthesis in Yeasts and Fungi; ; References; ; 15. Some Relations of Cholesterol to Other Lipids; ; I. Introduction; ; II. Interrelations with Other Lipids; ; III. Results from Balance Experiments; ; IV. The D Vitamins; ; V. General Conclusions; ; References; ; Appendix of Practical Methods; ; I. General; ; II. Extraction Procedures; ; III. Colorimetric Determinations; ; IV. Chromatography; ; V. Estimation of Serum Lipoproteins by Zone Electrophoresis and Estimation of Cholesterol; ; Author Index; ; Subject Index;
• Publisher Details: New York : Academic Press
• Publication Date: 2015
• Extent: 1 online resource, illustrations (black and white)
• Subjects: 612.01577; Cholesterol
• Languages: English
• ISBNs: 9781483271651
• Related ISBNs: 148327165X
• Notes: Note: Includes bibliographical references and index.
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.