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Author/Creator Sack, John S.

1. 9H-Carbazole-1-carboxamides as potent and selective JAK2 inhibitors. Issue 14 (15th July 2015)

Authors:
Zimmermann, Kurt; Sang, Xiaopeng; Mastalerz, Harold A.; Johnson, Walter L.; Zhang, Guifen; Liu, Qingjie; Batt, Douglas; Lombardo, Louis J.; Vyas, Dinesh; Trainor, George L.; Tokarski, John S.; Lorenzi, Matthew V.; You, Dan; Gottardis, Marco M.; Lippy, Jonathan; Khan, Javed; Sack, John S.; Puranda...
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 25:Issue 14(2015)
Page Start:
2809
Record Type:
Journal Article
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2. 9H-Carbazole-1-carboxamides as potent and selective JAK2 inhibitors. Issue 14 (15th July 2015)

Authors:
Zimmermann, Kurt; Sang, Xiaopeng; Mastalerz, Harold A.; Johnson, Walter L.; Zhang, Guifen; Liu, Qingjie; Batt, Douglas; Lombardo, Louis J.; Vyas, Dinesh; Trainor, George L.; Tokarski, John S.; Lorenzi, Matthew V.; You, Dan; Gottardis, Marco M.; Lippy, Jonathan; Khan, Javed; Sack, John S.; Puranda...
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 25:Issue 14(2015)
Page Start:
2809
Record Type:
Journal Article
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4. Discovery and SAR of pyrrolo[2, 1-f][1, 2, 4]triazin-4-amines as potent and selective PI3Kδ inhibitors. Issue 17 (1st September 2016)

Authors:
Bhide, Rajeev S.; Neels, James; Qin, Lan-Ying; Ruan, Zheming; Stachura, Sylwia; Weigelt, Carolyn; Sack, John S.; Stefanski, Kevin; Gu, Xiaomei; Xie, Jenny H.; Goldstine, Christine B.; Skala, Stacey; Pedicord, Donna L.; Ruepp, Stefan; Dhar, T.G. Murali; Carter, Percy H.; Salter-Cid, Luisa M.; Poss...
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 26:Issue 17(2016)
Page Start:
4256
Record Type:
Journal Article
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5. Discovery and structure-based design of 4, 6-diaminonicotinamides as potent and selective IRAK4 inhibitors. Issue 21 (1st November 2017)

Authors:
Bhide, Rajeev S.; Keon, Alec; Weigelt, Carolyn; Sack, John S.; Schmidt, Robert J.; Lin, Shuqun; Xiao, Hai-Yun; Spergel, Steven H.; Kempson, James; Pitts, William J.; Carman, Julie; Poss, Michael A.
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 27:Issue 21(2017)
Page Start:
4908
Record Type:
Journal Article
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6. Discovery of (3S, 4S)-3-methyl-3-(4-fluorophenyl)-4-(4-(1, 1, 1, 3, 3, 3-hexafluoro-2-hydroxyprop-2-yl)phenyl)pyrrolidines as novel RORγt inverse agonists. Issue 17 (1st September 2020)

Authors:
Jiang, Bin; Duan, James J.-W.; Stachura, Sylwia; Karmakar, Ananta; Hemagiri, Hemalatha; Raut, Dhanya Kumar; Gupta, Arun Kumar; Weigelt, Carolyn A.; Khan, Javed; Sack, John S.; Wu, Dauh-Rurng; Yarde, Melissa; Shen, Ding-Ren; Galella, Michael A.; Mathur, Arvind; Zhao, Qihong; Salter-Cid, Luisa M.; ...
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 30:Issue 17(2020)
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Journal Article
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7. Discovery of 2, 6–difluorobenzyl ether series of phenyl ((R)–3–phenylpyrrolidin–3–yl)sulfones as surprisingly potent, selective and orally bioavailable RORγt inverse agonists. Issue 19 (1st October 2020)

Authors:
Duan, James J.-W.; Jiang, Bin; Lu, Zhonghui; Stachura, Sylwia; Weigelt, Carolyn A.; Sack, John S.; Khan, Javed; Ruzanov, Max; Wu, Dauh–Rurng; Yarde, Melissa; Shen, Ding–Ren; Zhao, Qihong; Salter–Cid, Luisa M.; Carter, Percy H.; Murali Dhar, T.G.
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 30:Issue 19(2020)
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Journal Article
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8. Discovery of 7-(3-(piperazin-1-yl)phenyl)pyrrolo[2, 1-f][1, 2, 4]triazin-4-amine derivatives as highly potent and selective PI3Kδ inhibitors. Issue 4 (15th February 2017)

Authors:
Qin, Lan-Ying; Ruan, Zheming; Cherney, Robert J.; Dhar, T.G. Murali; Neels, James; Weigelt, Carolyn A.; Sack, John S.; Srivastava, Anurag S.; Cornelius, Lyndon A.M.; Tino, Joseph A.; Stefanski, Kevin; Gu, Xiaomei; Xie, Jenny; Susulic, Vojkan; Yang, Xiaoxia; Yarde-Chinn, Melissa; Skala, Stacey; Bo...
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 27:Issue 4(2017)
Page Start:
855
Record Type:
Journal Article
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9. Discovery of a phenylpyrazole amide ROCK inhibitor as a tool molecule for in vivo studies. Issue 21 (1st November 2020)

Authors:
Hu, Zilun; Wang, Cailan; Glunz, Peter W.; Li, Julia; Cheadle, Nathan L.; Chen, Alice Y.; Chen, Xue-Qing; Myers, Joseph E.; Guarino, Victor R.; Rose, Anne; Sack, John S.; Sitkoff, Doree; Taylor, David S.; Xu, Songmei; Yan, Chunhong; Zhang, Hongwei; Zhang, Lisa; Hennan, James; Adam, Leonard P.; Wex...
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 30:Issue 21(2020)
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Journal Article
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10. Discovery of highly potent, selective, covalent inhibitors of JAK3. Issue 20 (15th October 2017)

Authors:
Kempson, James; Ovalle, Damaso; Guo, Junqing; Wrobleski, Stephen T.; Lin, Shuqun; Spergel, Steven H.; Duan, James J.-W.; Jiang, Bin; Lu, Zhonghui; Das, Jagabandhu; Yang, Bingwei V.; Hynes, John; Wu, Hong; Tokarski, John; Sack, John S.; Khan, Javed; Schieven, Gary; Blatt, Yuval; Chaudhry, Charu; S...
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 27:Issue 20(2017)
Page Start:
4622
Record Type:
Journal Article
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