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- Ito, Kousei [remove] 20
- Toxicology -- Periodicals 10
- 615.9 8
- Toxicity testing -- In vitro -- Periodicals 7
- Chemicals -- Physiological effect -- Periodicals 3
- Drugs -- Metabolism -- Periodicals 3
- Pharmacokinetics -- Periodicals 3
- 615.7 2
- 615.9005 2
- Bile canaliculus -- Sandwich cultured hepatocytes -- Hepatotoxicity -- In vitro screening -- Cholestasis -- Jaundice 2
- DILI drug-induced liver injury -- ALT alanine aminotransferase -- ALP alkaline phosphatase -- BBW black box warning -- WDN withdrawn -- BC bile canalicular -- BSEP bile salt export pump -- MRP2 multidrug resistance-associated protein 2 -- SCHs sandwich cultured hepatocytes -- WME Williams' Medium E -- DMEM Dulbecco's Modified Eagle's Medium -- TCA taurocholic acid -- LCA lithocholic acid -- LDH lactate dehydrogenase -- IC50 half maximal inhibitory concentration -- FDA Food and Drug Administration -- MDD maximum daily dose -- PMDA Pharmaceuticals and Medical Devices Agency -- Cmax, u maximum unbound concentration in plasma -- NM no mention -- AR adverse reaction -- WNG warning -- PC precaution -- EC50 half maximal effective concentration 2