1. Conversion of carbazole carboxamide based reversible inhibitors of Bruton's tyrosine kinase (BTK) into potent, selective irreversible inhibitors in the carbazole, tetrahydrocarbazole, and a new 2, 3-dimethylindole series. Issue 18 (1st October 2018) Authors: Liu, Qingjie; Batt, Douglas G.; Chaudhry, Charu; Lippy, Jonathan S.; Pattoli, Mark A.; Surti, Neha; Xu, Songmei; Carter, Percy H.; Burke, James R.; Tino, Joseph A. Journal: Bioorganic & medicinal chemistry letters Issue: Volume 28:Issue 18(2018) Page Start: 3080 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
2. Design and synthesis of carbazole carboxamides as promising inhibitors of Bruton's tyrosine kinase (BTK) and Janus kinase 2 (JAK2). Issue 19 (1st October 2015) Authors: Liu, Qingjie; Batt, Douglas G.; Lippy, Jonathan S.; Surti, Neha; Tebben, Andrew J.; Muckelbauer, Jodi K.; Chen, Lin; An, Yongmi; Chang, Chiehying; Pokross, Matt; Yang, Zheng; Wang, Haiqing; Burke, James R.; Carter, Percy H.; Tino, Joseph A. Journal: Bioorganic & medicinal chemistry letters Issue: Volume 25:Issue 19(2015) Page Start: 4265 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
3. Design and synthesis of carbazole carboxamides as promising inhibitors of Bruton's tyrosine kinase (BTK) and Janus kinase 2 (JAK2). Issue 19 (1st October 2015) Authors: Liu, Qingjie; Batt, Douglas G.; Lippy, Jonathan S.; Surti, Neha; Tebben, Andrew J.; Muckelbauer, Jodi K.; Chen, Lin; An, Yongmi; Chang, Chiehying; Pokross, Matt; Yang, Zheng; Wang, Haiqing; Burke, James R.; Carter, Percy H.; Tino, Joseph A. Journal: Bioorganic & medicinal chemistry letters Issue: Volume 25:Issue 19(2015) Page Start: 4265 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
4. Discovery and SAR of pyrrolo[2, 1-f][1, 2, 4]triazin-4-amines as potent and selective PI3Kδ inhibitors. Issue 17 (1st September 2016) Authors: Bhide, Rajeev S.; Neels, James; Qin, Lan-Ying; Ruan, Zheming; Stachura, Sylwia; Weigelt, Carolyn; Sack, John S.; Stefanski, Kevin; Gu, Xiaomei; Xie, Jenny H.; Goldstine, Christine B.; Skala, Stacey; Pedicord, Donna L.; Ruepp, Stefan; Dhar, T.G. Murali; Carter, Percy H.; Salter-Cid, Luisa M.; Poss... Journal: Bioorganic & medicinal chemistry letters Issue: Volume 26:Issue 17(2016) Page Start: 4256 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
5. Discovery and synthesis of cyclohexenyl derivatives as modulators of CC chemokine receptor 2 activity. Issue 2 (15th January 2016) Authors: Brown, Gregory D.; Shi, Qing; Delucca, George V.; Batt, Douglas G.; Galella, Michael A.; Cvijic, Mary-Ellen; Liu, Rui-Qin; Qiu, Feng; Zhao, Qihong; Barrish, Joel C.; Carter, Percy H. Journal: Bioorganic & medicinal chemistry letters Issue: Volume 26:Issue 2(2016) Page Start: 662 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
6. Discovery of (3S, 4S)-3-methyl-3-(4-fluorophenyl)-4-(4-(1, 1, 1, 3, 3, 3-hexafluoro-2-hydroxyprop-2-yl)phenyl)pyrrolidines as novel RORγt inverse agonists. Issue 17 (1st September 2020) Authors: Jiang, Bin; Duan, James J.-W.; Stachura, Sylwia; Karmakar, Ananta; Hemagiri, Hemalatha; Raut, Dhanya Kumar; Gupta, Arun Kumar; Weigelt, Carolyn A.; Khan, Javed; Sack, John S.; Wu, Dauh-Rurng; Yarde, Melissa; Shen, Ding-Ren; Galella, Michael A.; Mathur, Arvind; Zhao, Qihong; Salter-Cid, Luisa M.; ... Journal: Bioorganic & medicinal chemistry letters Issue: Volume 30:Issue 17(2020) Page Start: Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
7. Discovery of 2, 6–difluorobenzyl ether series of phenyl ((R)–3–phenylpyrrolidin–3–yl)sulfones as surprisingly potent, selective and orally bioavailable RORγt inverse agonists. Issue 19 (1st October 2020) Authors: Duan, James J.-W.; Jiang, Bin; Lu, Zhonghui; Stachura, Sylwia; Weigelt, Carolyn A.; Sack, John S.; Khan, Javed; Ruzanov, Max; Wu, Dauh–Rurng; Yarde, Melissa; Shen, Ding–Ren; Zhao, Qihong; Salter–Cid, Luisa M.; Carter, Percy H.; Murali Dhar, T.G. Journal: Bioorganic & medicinal chemistry letters Issue: Volume 30:Issue 19(2020) Page Start: Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
8. Discovery of highly potent, selective, covalent inhibitors of JAK3. Issue 20 (15th October 2017) Authors: Kempson, James; Ovalle, Damaso; Guo, Junqing; Wrobleski, Stephen T.; Lin, Shuqun; Spergel, Steven H.; Duan, James J.-W.; Jiang, Bin; Lu, Zhonghui; Das, Jagabandhu; Yang, Bingwei V.; Hynes, John; Wu, Hong; Tokarski, John; Sack, John S.; Khan, Javed; Schieven, Gary; Blatt, Yuval; Chaudhry, Charu; S... Journal: Bioorganic & medicinal chemistry letters Issue: Volume 27:Issue 20(2017) Page Start: 4622 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
9. Discovery of potent and efficacious pyrrolopyridazines as dual JAK1/3 inhibitors. Issue 14 (15th July 2017) Authors: Hynes, John; Wu, Hong; Kempson, James; Duan, James J.-W.; Lu, Zhonghui; Jiang, Bin; Stachura, Sylwia; Tokarski, John S.; Sack, John S.; Khan, Javed A.; Lippy, Jonathan S.; Zhang, Rosemary F.; Pitt, Sidney; Shen, Guoxiang; Gillooly, Kate; McIntyre, Kim; Carter, Percy H.; Barrish, Joel C.; Nadler, ... Journal: Bioorganic & medicinal chemistry letters Issue: Volume 27:Issue 14(2017) Page Start: 3101 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
10. Identification and synthesis of potent and selective pyridyl-isoxazole based agonists of sphingosine-1-phosphate 1 (S1P1). Issue 10 (15th May 2016) Authors: Guo, Junqing; Watterson, Scott H.; Spergel, Steven H.; Kempson, James; Langevine, Charles M.; Shen, Ding Ren; Yarde, Melissa; Cvijic, Mary Ellen; Banas, Dana; Liu, Richard; Suchard, Suzanne J.; Gillooly, Kathleen; Taylor, Tracy; Rex-Rabe, Sandra; Shuster, David J.; McIntyre, Kim W.; Cornelius, Ge... Journal: Bioorganic & medicinal chemistry letters Issue: Volume 26:Issue 10(2016) Page Start: 2470 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗