Detection, Risk Assessment, and Survey of Four Polycyclic Aromatic Hydrocarbon Markers in Infant Formula Powder. (21st February 2020)

• Record Type: Journal Article
• Authors: Cai, Chenggang; Wu, Pinggu; Zhou, Pingping; Yang, Dajin; Hu, Zhengyan
• Other Names: Signes-Pastor Antonio J. Academic Editor.
• Is Part Of: Journal of food quality. Volume 2020(2020)
• Publication Date: 2020-02-21
• Subjects: Food industry and trade -- Quality control -- Periodicals; Food industry and trade -- Standards -- Periodicals; Food -- Periodicals; 664.07
• DOI: 10.1155/2020/2959532
• Languages: English
• ISSNs: 0146-9428

Abstract

Abstract : A gas chromatography-mass spectroscopy (GC-MS) method was developed to assess the infant exposure assessment from four important polycyclic aromatic hydrocarbon (PAH) markers in infant formula powder: benzo[a]anthracene, chrysene, benzo[b]fluoranthene, and benzo[a]pyrene (collectively referred to as PAH4). The developed method required the addition of an isotopically labeled internal standard, sample extraction under alkali conditions, a saponification step, and a solid-phase extraction purification step. In a controlled spike test, the average recovery rates of PAH4 were 77.3% to 111.8% and the relative standard deviations were 4.8% to 14.2% ( n = 6). The quantitative limit (LOQ) and detection limit (LOD) of the method were 0.5 and 0.1 μ g·kg −1, respectively. The PAH4 content was analyzed in 30 commercially available infant formula powders. The PAH4 content was found to be in the range of 0.1 to 0.87 μ g·kg −1 . Combined with the daily intake of infant milk powder in China, the average and maximum daily exposure of BaP for stage-1 infants in China are 0.45 ng/kg.bw.d −1 and 1.9 ng/kg.bw.d −1 and the PAH4 values are 8.6 ng/kg.bw.d −1 and 18.6 ng/kg.bw.d −1, respectively. The PAH4 content in the tested infant formula powders sold in the China were sufficiently low, and all of the tested products were safe for consumption.