Catalyst-free electrochemical trifluoromethylation of coumarins using CF3SO2NHNHBoc as the CF3 source. Issue 9 (14th February 2023)

• Record Type: Journal Article
• Authors: Cen, Nannan; Wang, Han; Zhou, YiCheng; Gong, Ruoqu; Sui, Dandan; Chen, Wenbo
• Is Part Of: Organic & biomolecular chemistry. Volume 21:Issue 9(2023)
• Page Start: 1883
• Page End: 1887
• Publication Date: 2023-02-14
• Subjects: Chemistry, Organic -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1039/d2ob01925f
• Languages: English
• ISSNs: 1477-0520

Abstract

Abstract : An efficient electrochemical trifluoromethylation of coumarins using CF3 SO2 NHNHBoc as the source of the trifluoromethyl group was developed. Abstract : An efficient electrochemical trifluoromethylation of coumarins using CF3 SO2 NHNHBoc as the source of the trifluoromethyl group was developed. Under catalyst-free and external oxidant-free electrolysis conditions, a range of 3-trifluoromethyl coumarins were obtained in moderate to good yields. The method could be easily scaled up with moderate efficiency.