A Decade of EEG Theta/Beta Ratio Research in ADHD: A Meta-Analysis. (July 2013)

• Record Type: Journal Article
• Authors: Arns, Martijn; Conners, C. Keith; Kraemer, Helena C.
• Is Part Of: Journal of attention disorders. Volume 17:Number 5(2013)
• Page Start: 374
• Page End: 383
• Publication Date: 2013-07
• Subjects: ADHD -- EEG -- QEEG -- theta -- beta -- Theta/Beta ratio -- neurofeedback; Attention-deficit hyperactivity disorder -- Periodicals; Attention -- Periodicals; 616.8589
• DOI: 10.1177/1087054712460087
• Languages: English
• ISSNs: 1087-0547

Abstract

Objective: Many EEG studies have reported that ADHD is characterized by elevated Theta/Beta ratio (TBR). In this study we conducted a meta-analysis on the TBR in ADHD.Method: TBR data during Eyes Open from location Cz were analyzed from children/adolescents 6-18 years of age with and without ADHD.Results: Nine studies were identified with a total of 1253 children/adolescents with and 517 without ADHD. The grand-mean effect size (ES) for the 6-13 year-olds was 0.75 and for the 6-18 year-olds was 0.62. However the test for heterogeneity remained significant; therefore these ESs are misleading and considered an overestimation. Post-hoc analysis found a decreasing difference in TBR across years, explained by an increasing TBR for the non-ADHD groups.Conclusion: Excessive TBR cannot be considered a reliable diagnostic measure of ADHD, however a substantial sub-group of ADHD patients do deviate on this measure and TBR has prognostic value in this sub-group, warranting its use as a prognostic measure rather than a diagnostic measure.