Bixin-loaded colloidal nanodelivery systems, techniques and applications. (30th June 2023)

• Record Type: Journal Article
• Authors: Enayati, Ayesheh; Rezaei, Atefe; Falsafi, Seid Reza; Rostamabadi, Hadis; Malekjani, Narjes; Akhavan-Mahdavi, Sahar; Kharazmi, Mohammad Saeed; Jafari, Seid Mahdi
• Is Part Of: Food chemistry. Volume 412(2023)
• Publication Date: 2023-06-30
• Subjects: Bixin -- Nanoencapsulation -- Nanocarriers -- Bioavailability -- Food industry -- Health benefits; Food -- Analysis -- Periodicals; Food -- Composition -- Periodicals; 664
• DOI: 10.1016/j.foodchem.2023.135479
• Languages: English
• ISSNs: 0308-8146

Abstract

Graphical abstract: Highlights: Encapsulation and nanodelivery systems shield bixin shelf life, color and bioavailability against oxygen, light, pHs, and heat. Encapsulation enhances water solubility of bixin. Encapsulated bixin shows a sustainable release, efficiency and dispersion stability. Abstract: Bixin is the cis -carotenoid from the seed of achiote tree or annatto. It is an approved liposoluble apocarotenoid by FDA as colorant and additive in the food industry. Nonetheless, bixin is unstable in the presence of oxygen, light, high pHs (alkali) and heat; thereby reducing its bioavailability/bioactivity, and also, with a low solubility in water. Some biopolymeric (e.g., nanofibers, nanogels, and nanotubes) and lipid-based nanocarriers (nanoliposomes, niosomes, hexosomes, nanoemulsions, solid-lipid nanoparticles, and nanostructured lipid carriers) have been introduced for bixin. Thus, this review focuses on the updated information regarding bixin-loaded nanodelivery platforms. Moreover, it provides a comprehensive review of bioavailability, physicochemical properties, and applications of nanoencapsulated-bixin as an additive, its release rate and safety issues. These findings will bring potential strategies for the usage of nanocarriers in managing bixin defaults to improve its broad application in various industries.