A Case of Adalimumab-Induced Pneumonitis in a 45-Year-Old Man with Crohn's Disease. Issue 5 (2011)

• Record Type: Journal Article
• Authors: Reid, James D; Bressler, Brian; English, John
• Is Part Of: Canadian respiratory journal. Volume 18:Issue 5(2011)
• Page Start: 262
• Page End: 264
• Publication Date: 2011
• Subjects: Acute drug reaction -- Adalimumab -- Antitumour necrosis factor-alpha -- Drug-induced lung disease -- Drug-induced lung toxicity -- Interstitial lung disease; Respiratory organs -- Diseases -- Periodicals; Respiration -- Canada -- Periodicals; Respiration; Respiratory organs -- Diseases; Canada; Respiratory Tract Diseases -- Periodicals; Periodicals; Periodicals; 616.2
• DOI: 10.1155/2011/713821
• Languages: English
• ISSNs: 1198-2241

Abstract

Abstract : Adalimumab is a human monoclonal antibody against tumour necrosis factor-alpha that has been associated with acute lung toxicity, mainly in patients with rheumatoid arthritis. Descriptions of similar patterns of lung injury in patients treated with adalimumab for inflammatory bowel disease are emerging in the literature. A case involving a 45-year-old man with Crohn's disease who developed a nonbronchiolitis inflammatory nodular pattern of lung injury after starting adalimumab is reported.