Systematic Review and Meta-Analysis on the Effect of Portion Size and Ingestive Frequency on Energy Intake and Body Weight among Adults in Randomized Controlled Feeding Trials. Issue 1 (23rd October 2021)

• Record Type: Journal Article
• Authors: Higgins, Kelly A; Hudson, Joshua L; Hayes, Anna M R; Braun, Ethan; Cheon, Eunjin; Couture, Sam C; Gunaratna, Nilupa S; Hill, Erica R; Hunter, Stephanie R; McGowan, Bethany S; Reister, Evan J; Wang, Yu; Mattes, Richard D
• Is Part Of: Advances in nutrition. Volume 13:Issue 1(2022)
• Page Start: 248
• Page End: 268
• Publication Date: 2021-10-23
• Subjects: ingestive behavior -- serving size -- food intake -- feeding pattern -- healthy population -- normal weight -- overweight -- obese; Nutrition -- Periodicals; Diet therapy -- Periodicals; Nutrition; Nutritional Physiological Phenomena; Nutritional Sciences; Periodicals; 613.205
• DOI: 10.1093/advances/nmab112
• Languages: English
• ISSNs: 2161-8313

Abstract

ABSTRACT: Energy intake is the product of portion size (PS)—the energy content of an ingestive event—and ingestive frequency (IF)—the number of ingestive events per unit time. An uncompensated alteration in either PS or IF would result in a change in energy intake and body weight if maintained over time. The objective of this meta-analysis was to assess the independent effects of PS and IF on energy intake and body weight among healthy adults in randomized controlled trials (RCTs). A total of 9708 articles were identified in PubMed, Web of Science, Cochrane, and CINAHL databases. The articles were divided among 10 researchers; each article was screened for eligibility by 2–3 independent reviewers. Exclusion criteria included: populations <19 y and >65 y, unhealthy populations (i.e. participants with an acute or chronic disease), assessments <24 h and <4 wk in duration for trials investigating energy intake or body weight, respectively. Controlled feeding trials (i.e. fixed energy intake) that manipulated IF and PS in the same study intervention (IF/PS) were evaluated separately and for the body weight outcome only. Twenty-two studies (IF = 4, PS = 14, IF/PS = 4) met the inclusion criteria. There was an insufficient number of studies to assess the effect of IF, PS, or IF/PS on body weight. There was heterogeneity in the effect sizes among all comparisons ( I 2 ≥75%). Consuming larger portion sizes was associated with higher daily energy intake [295 kcal (202, 388), n = 24; weighted mean differences (WMD) (95% CI), n = comparisons], and increased frequency of ingestive events was associated with higher energy intake [203 kcal (76, 330), n = 10]. Results from RCTs support that larger PS and greater IF are both associated with higher energy consumption. However, there is insufficient information to determine chronic effects on body weight. This protocol was registered at the International Prospective Register of Systematic Reviews (PROSPERO) as CRD42018104757. Abstract : Statement of Significance : Results from this systematic review and meta-analysis reveal that both larger portion sizes and increased ingestive frequency are associated with higher total daily energy intake in randomized controlled trials among healthy adults, yet there were an insufficient number of published studies to determine whether the short-term increases in energy intake would influence body weight if maintained long term.