Cu2+ assisted carnation-like fluorescent metal–organic framework for triple-mode detection of glyphosate in food samples. (15th May 2023)

• Record Type: Journal Article
• Authors: Guan, Jianping; He, Qing; Liu, Qi; Chen, Xiaoqing
• Is Part Of: Food chemistry. Volume 408(2023)
• Publication Date: 2023-05-15
• Subjects: Glyphosate -- Metal-organic framework -- Multiple-mode detection -- POCT -- Food analysis; Food -- Analysis -- Periodicals; Food -- Composition -- Periodicals; 664
• DOI: 10.1016/j.foodchem.2022.135237
• Languages: English
• ISSNs: 0308-8146

Abstract

Highlights: A luminescent ligand H2 L was designed and synthesized to contain 3 functional parts. A novel carnation-like LMOF IRMOF-3-L was fabricated via binding H2 L with Zn 2+ . The IRMOF-3-L/Cu 2+ had unique peroxidase-like activity and fluorescence property. Triple-model (colorimetric/fluorescent/SERS) detection of Glyp in food was realized. A test strips-smartphone sensing platform was developed for POCT of Glyp in food. Abstract: Herein, by employing a novel synthesized ligand H2 L, a flower-like luminescent metal–organic framework IRMOF-3-L was constructed for developing a triple-mode sensor for glyphosate (Glyp) detection. The ligand H2 L was designed to contain three functional parts, which endowed the resulted IRMOF-3-L with peroxidase-like activity and unique fluorescence property, as well as specific combining capacity for Cu 2+ to quench its fluorescence. The quenched fluorescence of IRMOF-3-L/Cu 2+ could be recovered by Glyp to realize fluorescence detection of Glyp. Besides, the peroxidase activity of IRMOF-3-L/Cu 2+ could also be inhibited by Glyp, and result in the decrease of catalysate oxTMB, concurrently reducing the changes of colorimetric and SERS signal. Therefore, the fluorescent/colorimetric/SERS triple-mode based detection of Glyp was favorably realized, and the detection limits were calculated as low as 0.738, 2.26 and 0.186 nM, respectively. Furthermore, a portable test strips-smartphone sensing platform was constructed for point of care testing of Glyp in food samples.