Could foodomics hold the key to unlocking the role of prebiotics in gut microbiota and immunity?. (December 2022)

• Record Type: Journal Article
• Authors: Lee Nen That, Lisa FM; Xu, Baojun; Pandohee, Jessica
• Is Part Of: Current opinion in food science. Volume 48(2022)
• Publication Date: 2022-12
• Subjects: Food -- Microbiology -- Periodicals; Food -- Analysis -- Periodicals; Food -- Biotechnology -- Periodicals; Food -- Periodicals; Food -- Research -- Periodicals; Nutrition -- Periodicals; Food -- Biotechnology; Food -- Microbiology; Food -- Analysis; Food; Food -- Research; Nutrition; Food Technology -- Periodicals; Food Analysis -- Periodicals; Food Microbiology -- Periodicals; Periodicals; Electronic journals; 641.3
• DOI: 10.1016/j.cofs.2022.100920
• Languages: English
• ISSNs: 2214-7993

Abstract

Abstract : Prebiotics research in the last decade has come a long way due to the maturation of omics technologies (genomics, transcriptomics, proteomics, metabolomics, and foodomics) and bioinformatics tools. Nowadays, prebiotics are not only thought of as oligosaccharides, but several classes of compounds that have been proven to have prebiotic characteristics and thousands of new sources of prebiotics are still under exploration. The discovery of novel prebiotics means that further research is needed to understand their roles in the microbiota and the host. The relationship between the gut microbiota and its host is crucial in determining the host well-being and the ability of the microbiota to thrive. A dysbiosis in this relationship can cause severe illnesses. This review discusses how omics technologies can be used in prebiotics research. Highlights: Foodomics is revolutionizing the study of eprebiotic–microbiota–host interactions Mechanistic studies will identify the functions of prebiotics and probiotics An immune homeostasis in the gut microbiota is imperative for gut immunity.