Rational construction of a robust nanoprobe for highly selective and sensitive nitrite and formaldehyde detection and imaging in real foods. (30th March 2023)

• Record Type: Journal Article
• Authors: Tan, Libin; Xie, Can; Yang, Qiaomei; Luo, Kun; Zhou, Liyi
• Is Part Of: Food chemistry. Volume 405:Part B(2023)
• Publication Date: 2023-03-30
• Subjects: Nitrite -- Formaldehyde -- Food hazards -- Nanoprobe; Food -- Analysis -- Periodicals; Food -- Composition -- Periodicals; 664
• DOI: 10.1016/j.foodchem.2022.134949
• Languages: English
• ISSNs: 0308-8146

Abstract

Highlights: A host–guest self-assembly nanoprobe MTB was constructed for NO2 – and FA detection. MTB can report FA, NO2 –, and FA/NO2 – with different optical signals. MTB was successfully adopted to detect FA and NO2 – in real foods samples. Abstract: Nitrite (NO2 – ) and formaldehyde (FA) are practice common food hazards, seriously threatening human health. Herein, for the first time a de novo nanoprobe, named MTB, with a single response group exhibiting different optical signals for NO2 – /FA was reported, which had the following characteristics: i) An adamantane-labeled small molecule NI-adH grafted with polycyclodextrin (Poly-β-CD) to form MTB with excellent water-solubility and biocompatibility. ii) O -phenylenediamine (OPD) with photoinduced electron transfer (PET) played both a fluorescence quencher and as NO2 – /FA trappers. Interestingly, fixed on pH6.0, OPD rapidly reacted with NO2 – forming triazoles, inhibiting the PET effect and releasing bright fluorescence at 530 nm. While adding FA, OPD ultrafast formed Schiff-base, and MTB absorption red-shifted from 452 nm to 545 nm. Moreover, MTB exhibited excellent selectivity, high sensitivity (21.8 nM/17.1 nM), and rapid response towards (60 s/65 s) NO2 – /FA. Impressively, MTB has been successfully adopted to detect NO2 – /FA in real foods with satisfactory results.