Markov Jump Processes: The Augmented Jump Chain (Adv. Theory Simul. 4/2021). Issue 4 (10th April 2021)

• Record Type: Journal Article
• Authors: Sikorski, Alexander; Weber, Marcus; Schütte, Christof
• Is Part Of: Advanced theory and simulations. Volume 4:Issue 4(2021)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2021-04-10
• Subjects: Science -- Simulation methods -- Periodicals; Science -- Methodology -- Periodicals; Engineering -- Simulation methods -- Periodicals; Engineering -- Methodology -- Periodicals; 507.21
• DOI: 10.1002/adts.202170007
• Languages: English
• ISSNs: 2513-0390

Abstract

Abstract : The picture shows a transmembrane receptor located at the surface of a cell. It is the µ‐opioid receptor, which is responsible for suppressing pain sensations. It is important to know how probable it is that a pain relieve drug (pink, fentanyl) will bind to and activate the receptor. The augmented jump chain described in article 2000274 by Alexander Sikorski, Marcus Weber, and Christof Schütte offers a possible mathematical framework for answering this question.