Markov Jump Processes: The Augmented Jump Chain (Adv. Theory Simul. 4/2021). Issue 4 (10th April 2021) - Sikorski, Alexander
Abstract : The picture shows a transmembrane receptor located at the surface of a cell. It is the µ‐opioid receptor, which is responsible for suppressing pain sensations. It is important to know how probable it is that a pain relieve drug (pink, fentanyl) will bind to and activate the receptor. The augmented jump chain described in article 2000274 by Alexander Sikorski, Marcus Weber, and Christof Schütte offers a possible mathematical framework for answering this question.