Inside Front Cover: Species Differences in in vitro and Estimated in vivo Kinetics for Intestinal Microbiota Mediated Metabolism of Acetyl‐deoxynivalenols. Issue 9 (10th May 2021)

• Record Type: Journal Article
• Authors: Jin, Jing; Spenkelink, Albertus; Beekmann, Karsten; Baccaro, Marta; Xing, Fuguo; Rietjens, Ivonne M. C. M.
• Is Part Of: Molecular nutrition & food research. Volume 65:Issue 9(2021)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2021-05-10
• Subjects: Food -- Biotechnology -- Periodicals; Food -- Microbiology -- Periodicals; Nutrition -- Periodicals; Food -- Toxicology -- Periodicals; Nutrition -- Periodicals; Food Microbiology -- Periodicals; Food Technology -- Periodicals; Molecular Biology -- Periodicals; 664.0705
• DOI: 10.1002/mnfr.202170020
• Languages: English
• ISSNs: 1613-4125

Abstract

Abstract : Mol. Nutr. Food Res . 2021, 65, 2001085 DOI: 10.1002/mnfr.202001085 An in vitro anaerobic fecal incubation method is used to reveal the transformation rate of 3‐acetyl‐DON and 15‐acetyl‐DON by mouse, rat, pig, and human feces. The kinetic parameters for the de‐acetylation rate are converted to the in vivo catalytic efficiencies. It is concluded that interspecies differences in deacetylation exist, but that for all species in vivo deacetylated will be complete. This is reported by Jing Jin, Albertus Spenkelink, Karsten Beekmann, Marta Baccaro, Fuguo Xing, Ivonne M. C. M. Rietjens in article number 2001085 .