Novel molecularly imprinted phenolic resin–dispersive filter extraction for rapid determination of perfluorooctanoic acid and perfluorooctane sulfonate in milk. (30th January 2023)

• Record Type: Journal Article
• Authors: Ren, Jing; Lu, Yanke; Han, Yehong; Qiao, Fengxia; Yan, Hongyuan
• Is Part Of: Food chemistry. Volume 400(2023)
• Publication Date: 2023-01-30
• Subjects: ATR attenuated total reflectance -- BET Brunauer-Emmett-Teller -- COFs covalent organic frameworks -- DFE dispersive filter extraction -- d-SPE dispersive solid-phase extraction -- ESI electrospray ionization -- FT-IR fourier-transform infrared -- GC-MS gas chromatography-mass spectrometry -- LC-MS/MS liquid chromatography-tandem mass spectrometry -- LODs limits of detection -- LOQs limits of quantification -- MIP molecularly imprinted polymers -- MIP-PR molecularly imprinting phenolic resin -- NIP-PR non-molecularly imprinting phenolic resin -- MOFs metal-organic frameworks -- MRM multiple reaction monitoring -- PFNA perfluorononanoic acid -- PFOA perfluorooctanoic acid -- PFOS perfluorooctane sulfonate -- r correlation coefficient -- RSDs relative standard deviations -- SEM scanning electron microscopy -- SPE solid-phase extraction -- SPME solid-phase microextraction; Molecularly imprinted polymer -- Sample preparation -- Liquid chromatography-tandem mass spectrometry -- Perfluorinated compounds -- Food analysis; Food -- Analysis -- Periodicals; Food -- Composition -- Periodicals; 664
• DOI: 10.1016/j.foodchem.2022.134062
• Languages: English
• ISSNs: 0308-8146

Abstract

Highlights: MIP-PR prepared at room temperature recognised PFOA and PFOS. MIP-PR had the advantages of large surface area, easy synthesis, and low cost. MIP-PR had large adsorption capacity, strong selectivity, and rapid mass transfer. MIP-PR-DFE allowed extraction of PFOA and PFOS from milk in 5 min. MIP-PR-DFE-LC-MS/MS provided a new idea for the analysis of PFOA and PFOS. Abstract: Perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS) are emerging pollutants that threaten food safety. Herein, a rapid, accurate, and selective method for determination of PFOA and PFOS in milk was established by using new molecularly imprinted phenolic resin (MIP-PR) as the adsorbent of dispersive filter extraction (DFE) combined with liquid chromatography-tandem mass spectrometry (LC-MS/MS). MIP-PR was synthesized at room-temperature using m-aminophenol, glutaraldehyde, and perfluorononanoic acid as the monomers, cross-linkers, and virtual templates, respectively, and exhibited rapid mass transfer (30 s), high selectivity (imprinted factors > 3.7), and large adsorption capacity (>54.6 mg/g). Compared with reported methods, the developed MIP-PR–DFE method is fast, selective, inexpensive, and shows good purification and enrichment efficiency. The proposed MIP-PR–DFE–LC-MS/MS exhibited low limits of detection (0.006–0.022 ng/mL), high recoveries (94.7–109 %), and good precision (RSDs ≤ 9.5 %). This study provides a new idea for the development of imprinted resin adsorbents for perfluorinated compound, and a new method for sample pretreatment for monitoring of PFOA and PFOS in food.