Dietary exposure and risk assessment of phthalic acid esters through a total diet study in Shenzhen, South China. Issue 9 (2nd September 2022)

• Record Type: Journal Article
• Authors: Li, Zhong-Yi; Liu, Huan; Liu, Hui; Huang, Wei; Chu, Yue; Huang, Zhuo-Quan; Liu, Chun-Hong
• Is Part Of: Food additives & contaminants. Volume 39:Issue 9(2022)
• Page Start: 1591
• Page End: 1603
• Publication Date: 2022-09-02
• Subjects: Phthalate esters -- total diet study -- dietary exposure; Food additives -- Periodicals; Food contamination -- Periodicals; 664.06
• DOI: 10.1080/19440049.2022.2094474
• Languages: English
• ISSNs: 1944-0049

Abstract

Abstract: Phthalic acid esters (PAEs) are typical endocrine disruptors which are ubiquitous contaminants. Human exposure to PAEs is through multiple routes of which the diet is recognised as the main source of daily intake. The aim of this study was to evaluate the dietary exposure to PAEs of residents in Shenzhen (China) through a total diet study and assess the potential health risk. A total of 16 different phthalate esters in samples of 12 composite food groups were determined by GC–MS. The main dietary sources of PAE exposure among adult residents in Shenzhen were potatoes (21%), eggs (21%), meat (15%) and aquatic products (14%). The median total dietary exposure to PAEs in Shenzhen residents was 7780 ng kg −1 bw d −1, and the hazard quotients (HQ) of dimethyl phthalate (DMP), diethyl phthalate (DEP), di-isobutyl phthalate (DIBP), dibutyl phthalate (DBP) and di-2-ethylhexyl phthalate (DEHP) were 0.09, 0.06, 0.07, 0.10 and 0.03, respectively. Therefore, the risks from dietary PAE exposure were low. However, with the increasing use of PAEs and their accumulation in the environment, the probability of PAEs entering the food chain is gradually increasing and, therefore, PAEs should be strictly controlled and regularly monitored.