Young astringent persimmon tannin inhibits methicillin-resistant Staphylococcus aureus isolated from pork. (February 2019)

• Record Type: Journal Article
• Authors: Liu, Miaomiao; Yang, Kun; Wang, Jing; Zhang, Jie; Qi, Yiman; Wei, Xinyuan; Fan, Mingtao
• Is Part Of: Lebensmittel-Wissenschaft + Technologie =. Volume 100(2019)
• Page Start: 48
• Page End: 55
• Publication Date: 2019-02
• Subjects: Persimmon tannin -- Antibacterial mechanism -- Methicillin-resistant Staphylococcus aureus -- Cellular damage; Food industry and trade -- Periodicals; Food -- Composition -- Periodicals; Microbiology -- Periodicals; Nutrition -- Periodicals; 664.005
• DOI: 10.1016/j.lwt.2018.10.047
• Languages: English
• ISSNs: 0023-6438

Abstract

Abstract: Persimmon tannin (PT), a primary physiological component of young persimmon, exhibits antibacterial activity against several microorganisms, but its effect on methicillin-resistant Staphylococcus aureus (MRSA) remains unclear. In this study, we found that PT from young astringent persimmon fruit had an active inhibition against several MRSA isolated from retail pork and the minimum inhibitory concentrations were 1000 μg/mL. Treatment of PT suppressed cell proliferation, caused decreases in membrane potential and intracellular ATP concentration, destroyed whole cell protein integrity, and induced S phase cell cycle arrest. Electron microscopy demonstrated that PT can change the normal morphology of MRSA and cause severe damage on cell wall and cell membrane. These results indicated that PT presented antimicrobial activity against foodborne MRSA and could be potentially developed as an alternative or supplemental agent to control the spread and infection of MRSA in foods. Highlights: The antimicrobial activity of young persimmon tannin against MRSA was investigated. Young persimmon tannin showed growth inhibitory effect on MRSA. Young persimmon tannin induced cell membrane dysfunction. Young persimmon tannin led to whole cell protein and cell cycle depression. Young persimmon tannin caused cellular morphology alterations.