Controlled release of riboflavin encapsulated in pea protein microparticles prepared by emulsion-enzymatic gelation process. (March 2021)

• Record Type: Journal Article
• Authors: Djoullah, Attaf; Saurel, Rémi
• Is Part Of: Journal of food engineering. Volume 292(2021)
• Publication Date: 2021-03
• Subjects: Riboflavin -- Pea proteins -- Emulsion -- Transglutaminase -- Encapsulation -- Release; Food industry and trade -- Periodicals; Food -- Analysis -- Periodicals; Aliments -- Industrie et commerce -- Périodiques; Aliments -- Analyse -- Périodiques; Aliments -- Recherche -- Périodiques; 664.005
• DOI: 10.1016/j.jfoodeng.2020.110276
• Languages: English
• ISSNs: 0260-8774

Abstract

Abstract: Riboflavin was encapsulated in pea protein microparticles crosslinked by transglutaminase and the release properties of this system was studied in simulated gastric (pH = 1.2) and intestinal (pH = 7.4) fluids. The microparticles were obtained from a water-in-oil emulsion and subsequent enzymatic gelation. In presence of polyglycerol polyricinoleate as hydrophobic surfactant, magnetic agitation was preferred to high-speed homogenization in order to form spherical microparticles of ~150 μm average size. The encapsulation efficiency of crystallized riboflavin (RF) varied from 74% to 84% depending on the amount of loaded RF (0.1–1.0 wt%). According to the kinetic power law model, the release mechanisms of riboflavin under simulated gastrointestinal conditions were governed by diffusion in absence of digestive enzymes and by a support degradation phenomenon in their presence. The designed microparticles represented a potential system for the delivery of riboflavin up to the intestinal digestion phase. Highlights: Pea protein microparticles were prepared from W/O emulsion and enzymatic crosslinking. Riboflavin (RF) was encapsulated in ~150 μm microparticles with a 74% minimum yield. RF release profiles in simulated gastric and intestinal fluids were obtained. RF release kinetics were adjusted by a semi-empirical power law model. RF release was controlled by matrix degradation particularly in intestinal condition.