Gene deletion in an Italian haemophilia B subject. Issue 4 (August 1985)

• Record Type: Journal Article
• Authors: Bernardi, F; del Senno, L; Barbieri, R; Buzzoni, D; Gambari, R; Marchetti, G; Conconi, F; Panicucci, F; Positano, M; Pitruzzello, S
• Is Part Of: Journal of medical genetics. Volume 22:Issue 4(1985)
• Page Start: 305
• Page End: 307
• Publication Date: 1985-08
• Subjects: Medical genetics -- Periodicals; 616.042
• DOI: 10.1136/jmg.22.4.305
• Languages: English
• ISSNs: 1468-6244

Abstract

Abstract : DNA from 20 Italian haemophilia B patients was analysed by the Southern blotting technique and hybridisation to a factor IX cDNA probe. A large deletion of factor IX gene was detected in one patient with antibodies to the infused factor; the EcoRI pattern of the other 19 subjects examined was normal.