Gene deletion in an Italian haemophilia B subject. Issue 4 (August 1985) - Bernardi, F
Abstract : DNA from 20 Italian haemophilia B patients was analysed by the Southern blotting technique and hybridisation to a factor IX cDNA probe. A large deletion of factor IX gene was detected in one patient with antibodies to the infused factor; the EcoRI pattern of the other 19 subjects examined was normal.