Release characteristics and bioaccessibility of lutein from calcium alginate hydrogels during simulated digestion in vitro. (22nd July 2022)

• Record Type: Journal Article
• Authors: Luo, Shuwei; Song, Jiangfeng; Xu, Pengxiang; Dai, Zhuqing; Wu, Caie; Li, Ying
• Is Part Of: International journal of food science & technology. Volume 57:Number 9(2022)
• Page Start: 6122
• Page End: 6129
• Publication Date: 2022-07-22
• Subjects: Alginate hydrogel -- bioaccessibility -- Ca2+ cross‐linked -- lutein -- release characteristics; Food industry and trade -- Periodicals; 664
• DOI: 10.1111/ijfs.15972
• Languages: English
• ISSNs: 0950-5423

Abstract

Summary: In this study, the release of lutein from calcium alginate hydrogels during simulated digestion in vitro was investigated. The results showed that the cross‐linked hydrogel with Ca 2+ concentration >7.5 mM had a large amount of lutein retained on the surface, and digestive enzymes caused rapid degradation of the hydrogel structure, resulting in a high initial release rate. The particle size of the digestate was the largest in the simulated small intestinal digestion stage, with the gradual degradation of the outer wall proteins of lutein nanoparticles, showing a decreasing trend in the colonic digestion stage. The hydrogel cross‐linked with high concentration of Ca 2+ mainly released lutein nanoparticles with small particle size. In the later stage, the probability of agglomeration between lutein nanoparticles increased. The cumulative release rate of lutein in the hydrogel with Ca 2+ concentration <7.5 mM was higher after digestion, but lutein retention was <80%. The formation of lutein mixed micelles was hindered by the hydrogel with a Ca 2+ content more than 7.5 mM, and lutein bioaccessibility was reduced. As a result, appropriate concentration of Ca 2+ cross‐linked hydrogel carrier improved lutein bioavailability while also extending the residence period. Abstract : Effects of different Ca 2+ cross‐linked sodium alginate hydrogels on the release characteristics and bioaccessability of lutein during simulated digestion in vitro .