Motor neuron disease (amyotrophic lateral sclerosis) arising from longstanding primary lateral sclerosis. Issue 6 (June 1995)

• Record Type: Journal Article
• Authors: Bruyn, R P; Koelman, J H; Troost, D; de Jong, J M
• Is Part Of: Journal of neurology, neurosurgery and psychiatry. Volume 58:Issue 6(1995)
• Page Start: 742
• Page End: 744
• Publication Date: 1995-06
• Subjects: Neurology -- Periodicals; Nervous system -- Surgery -- Periodicals; Psychiatry -- Periodicals; 616.8
• DOI: 10.1136/jnnp.58.6.742
• Languages: English
• ISSNs: 0022-3050

Abstract

Abstract : Three men were initially diagnosed as having primary lateral sclerosis (PLS), but eventually developed amyotrophic lateral sclerosis (ALS) after 7.5, 9, and at least 27 years. Non-familial ALS and PLS might be different manifestations of a single disease or constitute completely distinct entities. The clinical diagnosis of PLS predicts a median survival that is four to five times longer than in ALS.