Laparoscopy-Assisted versus Open Hepatectomy for Live Liver Donor: Systematic Review and Meta-Analysis. (7th November 2017)

• Record Type: Journal Article
• Authors: Zhang, Bin; Pan, Yu; Chen, Ke; Maher, Hendi; Chen, Ming-Yu; Zhu, He-Pan; Zhu, Yi-Bin; Dai, Yi; Chen, Jiang; Cai, Xiu-jun
• Other Names: Peltekian Kevork M. Academic Editor.
• Is Part Of: Canadian journal of gastroenterology & hepatology. Volume 2017(2017)
• Publication Date: 2017-11-07
• Subjects: Digestive organs -- Diseases -- Periodicals; Gastroenterology -- Periodicals; Digestive organs -- Diseases; Gastroenterology; Canada; Digestive System Diseases -- Periodicals; Gastroenterology -- Periodicals; Periodicals; Electronic journals; Fulltext; Internet Resources; Periodicals; 616.3
• DOI: 10.1155/2017/2956749
• Languages: English
• ISSNs: 2291-2789

Abstract

Abstract : Objective . To assess the feasibility, safety, and potential benefits of laparoscopy-assisted living donor hepatectomy (LADH) in comparison with open living donor hepatectomy (ODH) for liver transplantation. Background . LADH is becoming increasingly common for living donor liver transplant around the world. We aim to determine the efficacy of LADH and compare it with ODH. Methods . A systematic search on PubMed, Embase, Cochrane Library, and Web of Science was conducted in May 2017. Results . Nine studies were suitable for this analysis, involving 979 patients. LADH seemed to be associated with increased operation time (WMD = 24.85 min; 95% CI: −3.01~52.78, P = 0.08 ), less intraoperative blood loss (WMD = −59.92 ml; 95% CI: −94.58~−25.27, P = 0.0 007 ), similar hospital stays (WMD = −0.47 d; 95% CI: −1.78~0.83, P = 0.47 ), less postoperative complications (RR = 0.70, 95% CI: 0.51~0.94, P = 0.02 ), less analgesic use (SMD = −0.22; 95% CI: −0.44~−0.11, P = 0.04 ), similar transfusion rates (RR = 0.82; 95% CI: 0.24~3.12, P = 0.82 ), and similar graft weights (WMD = 7.31 g; 95% CI: −23.45~38.07, P = 0.64 ). Conclusion . Our results indicate that LADH is a safe and effective technique and, when compared to ODH.