Antioxidant and Cytotoxicological Effects of Aloe vera Food Supplements. (7th March 2017)

• Record Type: Journal Article
• Authors: López, Zaira; Núñez-Jinez, Gabriela; Avalos-Navarro, Guadalupe; Rivera, Gildardo; Salazar-Flores, Joel; Ramírez, José A.; Ayil-Gutiérrez, Benjamín A.; Knauth, Peter
• Other Names: Zeppa Giuseppe Academic Editor.
• Is Part Of: Journal of food quality. Volume 2017(2017)
• Publication Date: 2017-03-07
• Subjects: Food industry and trade -- Quality control -- Periodicals; Food industry and trade -- Standards -- Periodicals; Food -- Periodicals; 664.07
• DOI: 10.1155/2017/7636237
• Languages: English
• ISSNs: 0146-9428

Abstract

Abstract : Currently, food industries use supplements from Aloe vera as highly concentrated powders (starting products), which are added to the final product at a concentration of 1x, meaning 10 g/L for decolourized and spray-dried whole leaf powder (WLP) or 5 g/L for decolourized and spray-dried inner leaf powder (ILG) and also for nondecolourized and belt-dried inner leaf powder (ILF). Flavonoids, tannins, or saponins could not be detected for any starting product at this concentration and their total phenol concentration of 68–112 μ M gallate-eq. was much lower than in fresh extract; however, their antioxidant capacity of 90–123 μ M ascorbate-eq. for DPPH was similar to the fresh extract. Starting products, dissolved at 1x, had an aloin concentration of 0.04 to 0.07 ppm, a concentration much lower than the industry standard of 10 ppm for foodstuff. While decolourized starting products (i.e., treated with activated carbon) exhibited low cytotoxicity on HeLa cells (CC50 = 15 g/L ILG or 50 g/L WLP), ILF at CC50 = 1–5 g/L exhibited cytotoxic effects, that is, at concentrations even below the recommended for human consumption. Probable causes for the cytotoxicity of ILF are the exposure to high temperatures (70–85°C) combined with a high fibre content.