Feedforward and output–feedback control of the cell distribution in chemostat yeast fermentations. Issue 7 (2022)

• Record Type: Journal Article
• Authors: Jerono, P.; Schaum, A.; Meurer, T.
• Is Part Of: IFAC-PapersOnLine. Volume 55:Issue 7(2022)
• Page Start: 556
• Page End: 561
• Publication Date: 2022
• Subjects: Cell population balance models -- partial integro-differential equation -- yeast fermentation -- process control -- tracking control; Automatic control -- Periodicals; 629.805
• DOI: 10.1016/j.ifacol.2022.07.502
• Languages: English
• ISSNs: 2405-8963

Abstract

Abstract: A two-degree-of-freedom control strategy is developed and experimentally validated for a set-point change along a desired trajectory of the cell distribution in yeast fermentation. Based on a mathematical model of yeast growth and cell population dynamics, an inversion-based feedforward controller is designed, utilizing a transformation between the biomass concentration and the cell distribution at the equilibrium points. To take disturbances and model inaccuracies into account, the controller is extended by a feedback control law. The controller is applied to a lab-scale stirred tank reactor with Saccharomyces cerevisiae.