Separation and determination of fluindapyr enantiomers in cucumber and tomato and by supercritical fluid chromatography tandem mass spectrometry. (30th November 2022)

• Record Type: Journal Article
• Authors: Guo, Peilin; An, Xiaokang; Chen, Wuying; Pan, Xinglu; Li, Runan; Xu, Jun; Wu, Xiaohu; Zheng, Yongquan; Dong, Fengshou
• Is Part Of: Food chemistry. Volume 395(2022)
• Publication Date: 2022-11-30
• Subjects: Fluindapyr -- Enantioselectivity -- Cucumber -- Tomato -- Supercritical Fluid Chromatography Tandem Mass Spectrometry (SFC-MS/MS); SFC-MS/MS supercritical fluid chromatography tandem mass spectrometry -- HPLC high-performance liquid chromatography -- MeOH methanol -- ACN acetonitrile -- PSA primary secondary amine -- GCB graphitized carbon black -- ABPR automated back-pressure regulator -- ESI electrospray ionization -- MRM multiple-reaction monitoring -- LOQ limit of quantification -- RT retention times -- RSD relative standard deviation -- Rs resolution -- T1/2 half-life; Food -- Analysis -- Periodicals; Food -- Composition -- Periodicals; 664
• DOI: 10.1016/j.foodchem.2022.133571
• Languages: English
• ISSNs: 0308-8146

Abstract

Graphical abstract: Highlights: The absolute configuration of fluindapyr enantiomers was first confirmed. SFC-MS/MS was initially developed for detection of fluindapyr enantiomers. Enantioselective behaviors of fluindapyr in different organs and plants were various. Abstract: Fluindapyr is a pyrazolamide chiral fungicide of succinate dehydrogenase inhibitor (SDHIs) with two enantiomers. Pesticide enantiomers often exhibit different biological activities, toxicity due to their different enantioselectivity. Therefore, it is important to separate fluindapyr enantiomers and assess each enantiomer. In this study, fluindapyr enantiomers were baseline separated by supercritical fluid chromatography-mass spectrometry in 2 min. The limit of quantification (LOQ) of this method was 5 μg/kg. The developed method was applied to monitor the fluindapyr enantiomers in cucumber and tomato, the data showed that R- ( - )-fluindapyr was preferentially degraded in tomato leaves, S -(+)-fluindapyr was preferentially degraded in cucumber leaves, and fluindapyr enantiomers had no enantioselective degradation behavior in two fruits. It is proved again that enantiomers have different enantioselective degradation behavior with the different plant species and even to different parts of the same plant. The enantioselectivity is likely to be caused by different biodegradation enzyme systems.