Comparison of Different Disease-Specific Health-Related Quality of Life Measurements in Patients with Long-Term Noninvasive Ventilation. (15th May 2017)

• Record Type: Journal Article
• Authors: Oga, Toru; Taniguchi, Hiroyuki; Kita, Hideo; Tsuboi, Tomomasa; Tomii, Keisuke; Ando, Morihide; Kojima, Eiji; Tomioka, Hiromi; Taguchi, Yoshio; Kaji, Yusuke; Maekura, Ryoji; Hiraga, Toru; Sakai, Naoki; Kimura, Tomoki; Mishima, Michiaki; Windisch, Wolfram; Chin, Kazuo
• Other Names: Braido Fulvio Academic Editor.
• Is Part Of: Canadian respiratory journal. Volume 2017(2017)
• Publication Date: 2017-05-15
• Subjects: Respiratory organs -- Diseases -- Periodicals; Respiration -- Canada -- Periodicals; Respiration; Respiratory organs -- Diseases; Canada; Respiratory Tract Diseases -- Periodicals; Periodicals; Periodicals; 616.2
• DOI: 10.1155/2017/8295079
• Languages: English
• ISSNs: 1198-2241

Abstract

Abstract : Background . Two disease-specific questionnaires have been developed to assess health-related quality of life (HRQL) in patients with chronic respiratory failure: the Severe Respiratory Insufficiency (SRI) Questionnaire and the Maugeri Respiratory Failure (MRF) Questionnaire. We aimed to compare the characteristics of the SRI, MRF-26, and St. George's Respiratory Questionnaire (SGRQ) for use in patients with home noninvasive ventilation (NIV). Methods . Fifty-six outpatients receiving long-term NIV were recruited and underwent assessments of pulmonary function, arterial blood gas, HRQL, dyspnea, and psychological status. Results . Correlations of the SRI and MRF-26 with the SGRQ were modest. While pulmonary function was weakly related to only some domains of the SRI and MRF-26, the modified Medical Research Council (mMRC) dyspnea scale and Hospital Anxiety and Depression Scale (HADS) were significantly related to all domains of the SRI and MRF-26. Multiple regression analyses showed that HADS depression and mMRC accounted for 34% and 27% of the variance in the SRI, 24% and 37% in the MRF-26, and 17% and 46% in the SGRQ, respectively. Conclusions . The SRI and MRF-26 were reliable questionnaires for patients receiving long-term NIV. Dyspnea and psychological status were their main common determinants. The SRI covers more psychological health impairments than the MRF. This trial is registered with ClinicalTrials.gov Identifier: NCT00905476 .