Oat beta glucans anti-inflammatory actions in leg exercise stress. Issue 1 (14th April 2020)

• Record Type: Journal Article
• Authors: Thompson, Jennifer Creamer; Kirby, Timothy; DiSilvestro, Robert A.
• Is Part Of: Nutrition & food science. Volume 51:Issue 1(2021)
• Page Start: 1
• Page End: 9
• Publication Date: 2020-04-14
• Subjects: Exercise -- Inflammation -- Fiber -- Glucans -- Myeloperoxidase; Nutrition -- Periodicals; Food -- Periodicals; 664.005
• DOI: 10.1108/NFS-01-2020-0011
• Languages: English
• ISSNs: 0034-6659

Abstract

Abstract : Purpose: Dietary fiber is not traditionally considered to have anti-inflammatory actions in skeletal muscle. This study aims to test the hypothesis that oat β-glucans fiber intake can inhibit exercise-induced inflammation. Design/methodology/approach: Young adult males (age 18-30 years) consumed either oat bran β-glucans (2 × 1.5 g fiber/day) or placebo for 4 weeks (Trial 1: N = 11 for placebo, N = 9 for glucan; Trial 2: N = 7 for placebo, N = 8 for glucan). Muscle inflammatory stress was induced at baseline and post-intervention using a leg extension regimen. Findings: Ingestion of β-glucans, but not placebo, protected against inflammation based on subjective soreness scores (two trials), as well as on plasma myeloperoxidase readings (one trial). Scores were subject ratings from 0 (no soreness) to 10 (injury that impairs movement). Mean soreness score was lower at 48 h after exercise stress: post-glucan treatment vs pre-treatment: Trial 1: 1.9 + 2.4 vs 3.3 + 2.2 ( p = 0.05); Trial 2: 1.2 + 0.7 vs 3.9 + 2.7 ( p < 0.05). Myeloperoxidase just after exercise stress increased for both groups pre-treatment, but only for the placebo group post-treatment: 62 + 12 vs 81 + 15 ( p < 0.05). Originality/value: This pilot study found that at least one type of dietary fiber can exert anti-inflammatory effects in skeletal muscle.