Electrochemical selenium–π–acid promoted hydration of alkynyl phosphonates. Issue 54 (16th June 2022)

• Record Type: Journal Article
• Authors: Li, Bo; Zhou, Yunhao; Sun, Yanan; Xiong, Feng; Gu, Linghui; Ma, Wenbo; Mei, Ruhuai
• Is Part Of: Chemical communications. Volume 58:Issue 54(2022)
• Page Start: 7566
• Page End: 7569
• Publication Date: 2022-06-16
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/d2cc01901a
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : Unprecedented electrochemical selenium–π–acid promoted hydration of alkynes bearing a phosphonate auxiliary was described. Thus, valuable (hetero)aryl and alkyl ketones could be accessed under mild, metal- and external oxidant-free conditions. Abstract : An unprecedented electrochemical selenium–π–acid promoted hydration of internal alkynes bearing a phosphonate auxiliary was described. Thus, valuable (hetero)aryl and alkyl ketones could be accessed under mild, metal- and external oxidant-free conditions. This protocol features high atom-economy, good chemo- and regio-selectivity, excellent functional group tolerance and easily transformable products. Control experiments demonstrate that phosphonate assistance is essential for this transformation.