A new aliphatic alcohol and cytotoxic chemical constituents from Acorus gramineus rhizomes. Issue 9 (2nd September 2015)

• Record Type: Journal Article
• Authors: Kim, Ki Hyun; Kang, Hee Rae; Eom, Hee Jeong; Kim, Chung Sub; Choi, Sang Un; Lee, Kang Ro
• Is Part Of: Bioscience, biotechnology, and biochemistry. Volume 79:Issue 9(2015)
• Page Start: 1402
• Page End: 1405
• Publication Date: 2015-09-02
• Subjects: Acorus gramineus -- Araceae -- aliphatic alcohol -- cytotoxicity; Biotechnology -- Periodicals; Biochemistry -- Periodicals; 660.6
• DOI: 10.1080/09168451.2015.1031079
• Languages: English
• ISSNs: 0916-8451

Abstract

Abstract: A new aliphatic alcohol, (2 R, 6 R )-oct-7-ene-2, 6-diol (1 ), and seven other known compounds (2-8 ) were isolated from Acorus gramineus rhizomes. The structure of 1 was elucidated by a combination of extensive spectroscopic analyses, including 2D NMR, HR-MS, and the modified Mosher's method. Compounds 3-8 displayed consistent antiproliferative activities against the cell lines tested with IC50 values ranging from 7 to 48 μm.