A new aliphatic alcohol and cytotoxic chemical constituents from Acorus gramineus rhizomes. Issue 9 (2nd September 2015) - Kim, Ki Hyun
Abstract: A new aliphatic alcohol, (2 R, 6 R )-oct-7-ene-2, 6-diol (1 ), and seven other known compounds (2-8 ) were isolated from Acorus gramineus rhizomes. The structure of 1 was elucidated by a combination of extensive spectroscopic analyses, including 2D NMR, HR-MS, and the modified Mosher's method. Compounds 3-8 displayed consistent antiproliferative activities against the cell lines tested with IC50 values ranging from 7 to 48 μm.