Middle purity soy lecithin is appropriate for food grade nanoliposome: Preparation, characterization, antioxidant and anti-inflammatory ability. (30th September 2022)

• Record Type: Journal Article
• Authors: Li, Jinglei; Nan, Jian; Wu, Haishan; Park, Hyun Jin; Zhao, Qingsheng; Yang, Liu
• Is Part Of: Food chemistry. Volume 389(2022)
• Publication Date: 2022-09-30
• Subjects: Soy lecithin -- Purity -- Crocetin -- Bioactivities -- In vitro simulated digestion; Food -- Analysis -- Periodicals; Food -- Composition -- Periodicals; 664
• DOI: 10.1016/j.foodchem.2022.132931
• Languages: English
• ISSNs: 0308-8146

Abstract

Graphical abstract: Highlights: Soy lecithin of different purity is used to prepare nanoliposome. Crocetin is encapsulated in prepared nanoliposome for the first time. Chitosan coating enhances stability of crocetin and attenuates it's release profile. Nanoliposome retains the bio-activities of crocetin. Abstract: The purity of soy lecithin exerts significant impact on nanoliposome (NL) properties for food applications. In this study, three soy lecithin of different purity were used to prepare NL. LC-MS analysis confirmed soy lecithin of relatively low purify (50% and 70%) contains multiple natural phospholipids. NL produced by soy lecithin of middle purity (70%) is smaller and more stable than other counterparts. Ultimately, soy lecithin of 70% purity was selected to develop NL encapsulated crocetin (CR) as model payload and further coated by chitosan (CS). The structure characteristic, physicochemical properties, antioxidant activity and anti-inflammatory activity of crocetin nanoliposome (CR-NL) and chitosan coated crocetin nanoliposome (CS-CR-NL) were evaluated. NL encapsulation and CS coating significantly improve antioxidant and anti-inflammatory ability of CR, and prolong storage period of CR (p < 0.05). For food applications, soy lecithin of middle purity (70%) is cheaper and more appropriate than soy lecithin of high purity.