Characterization of hydrophilic and hydrophobic core-shell microcapsules prepared using a range of antisolvent approaches. (October 2022)

• Record Type: Journal Article
• Authors: Hu, Bing; Yang, Yisu; Han, Lingyu; Yang, Jixin; Zheng, Wenjie; Cao, Jijuan
• Is Part Of: Food hydrocolloids. Volume 131(2022)
• Publication Date: 2022-10
• Subjects: Zein -- Core-shell microparticle -- Hydrophilic-hydrophobic structure -- Restricted antisolvent; Hydrocolloids -- Periodicals; Food additives -- Periodicals; Colloïdes -- Périodiques; Aliments -- Additifs -- Périodiques; Colloids; Food additives; Periodicals; Electronic journals; 664.06
• DOI: 10.1016/j.foodhyd.2022.107750
• Languages: English
• ISSNs: 0268-005X

Abstract

Abstract: This study describes three straightforward approaches to leveraging gel network-restricted antisolvent precipitation techniques as a means of preparing hydrophilic hydrophobic core-shell microparticles. Briefly, hydrophilic polysaccharides (sodium alginate (ALG), κ-carrageenan (CAR), and agar (AG)) were utilized to prepare microgel beads that were then immersed in zein solutions (70% ethanol aqueous solution, 70% urea aqueous solution, and zein in 70% acetic acid, respectively), thereby facilitating the controlled, slow antisolvent precipitation of the protein layer on the microbead surfaces and inducing hydrophilic hydrophobic core-shell structure formation. This technique can be readily applied to a range of gelling systems and can be tailored to target particle sizes and shell thicknesses. The resultant core-shell particles offer great promise for controlled delivery of fragrances, drugs, or other bioactive compounds in an application-specific fashion, and can be individually tailored based upon the selected input concentrations and preparation methods. Importantly, this technique is generalizable and can be extended to prepare diverse particles with a range of core-shell structures produced from a wide assortment of hydrophobic materials. Graphical abstract: Image 1 Highlights: Core-shell microcapsules were prepared using a range of antisolvent approaches. Size and shell thickness of microcapsules can be regulated. Core-shell particles offer great promise for controlled delivery in an application-specific fashion.