An autophagy-inhibitory MOF nanoreactor for tumor-targeted synergistic therapy. (26th May 2022)
- Record Type:
- Journal Article
- Title:
- An autophagy-inhibitory MOF nanoreactor for tumor-targeted synergistic therapy. (26th May 2022)
- Main Title:
- An autophagy-inhibitory MOF nanoreactor for tumor-targeted synergistic therapy
- Authors:
- Liu, Xiaohan
Gao, Peng
Shi, Mingwan
Chen, Yuanyuan
Pan, Wei
Li, Na
Tang, Bo - Abstract:
- Abstract : A cell membrane-camouflaged MOF nanoreactor was developed for inhibiting autophagy and synergistically restraining tumor growth. Abstract : An autophagy-inhibitory metal–organic framework (MOF) nanoreactor was developed for tumor-targeted synergistic therapy. The nanoreactor could inhibit autophagy to enhance the glucose oxidase (GOx)-mediated starvation therapy. The H2 O2 generated in this process induced the polarization of macrophages to the M1 phenotype, which further enhanced the therapeutic effect.
- Is Part Of:
- Biomaterials science. Volume 10:Number 12(2022)
- Journal:
- Biomaterials science
- Issue:
- Volume 10:Number 12(2022)
- Issue Display:
- Volume 10, Issue 12 (2022)
- Year:
- 2022
- Volume:
- 10
- Issue:
- 12
- Issue Sort Value:
- 2022-0010-0012-0000
- Page Start:
- 3088
- Page End:
- 3091
- Publication Date:
- 2022-05-26
- Subjects:
- Biomedical materials -- Periodicals
610.28 - Journal URLs:
- http://pubs.rsc.org/en/journals/journalissues/bm ↗
http://www.rsc.org/ ↗ - DOI:
- 10.1039/d2bm00579d ↗
- Languages:
- English
- ISSNs:
- 2047-4830
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 2087.724000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 21821.xml