Bile Acid–Microbiome Interaction Promotes Gastric Carcinogenesis (Adv. Sci. 16/2022). Issue 16 (3rd June 2022)

• Record Type: Journal Article
• Authors: Wang, Shouli; Kuang, Junliang; Zhang, Hongwei; Chen, Wenlian; Zheng, Xiaojiao; Wang, Jieyi; Huang, Fengjie; Ge, Kun; Li, Mengci; Zhao, Mingliang; Rajani, Cynthia; Zhu, Jinshui; Zhao, Aihua; Jia, Wei
• Is Part Of: Advanced science. Volume 9:Issue 16(2022)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2022-06-03
• Subjects: Science -- Periodicals; 505
• DOI: 10.1002/advs.202270105
• Languages: English
• ISSNs: 2198-3844

Abstract

Abstract : New Strategy for the Prevention of Gastric Cancer Bile reflux can promote gastric carcinogenesis through activation of the IL‐6/JAK1‐STAT3 signaling pathway. Inhibition of STAT3 by cryptotanshinone can alleviate this carcinogenic effect, thus providing a new strategy for the prevention of gastric cancer associated with bile reflux. More details can be found in article number 2200263 by Aihua Zhao, Wei Jia, and co‐workers.