Bile Acid–Microbiome Interaction Promotes Gastric Carcinogenesis (Adv. Sci. 16/2022). Issue 16 (3rd June 2022) - Wang, Shouli
Abstract : New Strategy for the Prevention of Gastric Cancer Bile reflux can promote gastric carcinogenesis through activation of the IL‐6/JAK1‐STAT3 signaling pathway. Inhibition of STAT3 by cryptotanshinone can alleviate this carcinogenic effect, thus providing a new strategy for the prevention of gastric cancer associated with bile reflux. More details can be found in article number 2200263 by Aihua Zhao, Wei Jia, and co‐workers.