Phospholipid composition and fat globule structure II: Comparison of mammalian milk from five different species. (15th September 2022)

• Record Type: Journal Article
• Authors: Wei, Wei; Li, Dan; Jiang, Chenyu; Zhang, Xinghe; Zhang, Xue; Jin, Qingzhe; Zhang, Xi; Wang, Xingguo
• Is Part Of: Food chemistry. Volume 388(2022)
• Publication Date: 2022-09-15
• Subjects: FA fatty acid -- GPL glycerophospholipid -- LCFA long-chain fatty acid -- LC-PUFA longchain polyunsaturated fatty acid -- Lyso-GPL lysoglycerophospholipid -- Lyso-PC lysophosphatidylcholine -- Lyso-PE lysophosphatidylethanolamine -- MCFA medium-chain fatty acid -- MUFA monounsaturated fatty acid -- SFA saturated fatty acid -- PA phosphatidic acid -- PC phosphatidylcholine -- PE phosphatidylethanolamine -- PEP phosphatidylethanolamine plasmalogen -- PG phosphatidylglycerol -- PI phosphatidylinositol -- PL phospholipids -- PS phosphatidylserine -- PUFA polyunsaturated fatty acid -- SCFA short-chain fatty acid -- SM sphingomyelin -- TAG triacylglycerol -- UFA unsaturated fatty acid; Milk fat globule -- Polar lipids -- Sphingomyelin -- Tandem mass spectrometry -- Membrane lipids -- Microstructure; Food -- Analysis -- Periodicals; Food -- Composition -- Periodicals; 664
• DOI: 10.1016/j.foodchem.2022.132939
• Languages: English
• ISSNs: 0308-8146

Abstract

Highlights: Phospholipids and milk fat globules were compared between five mammalian milk. Human milk contains a higher amount of sphingomyelin than other mammalian milk. The phospholipids acyl chain unsaturation are highest in human milk. Milk fat globules mean size and distribution showed obvious differences across species. A similar TAG core-membrane lipid structure was observed in all mammalian milk. Abstract: We compared phospholipids (PLs) content, their molecular species, and milk fat globules size and microstructure in the milk of five mammalian species, including human, cow, goat, yak, and donkey. The absolute quantification of major PLs was determined using 31 P NMR and their fatty acid composition with GC. The molecular species of PLs were analysed using LC-MS where a total of 9 PL species, including one sphingomyelin (SM), six glycerophospholipid (GPL), and two lysoglycerophospholipids (lyso-GPLs), were identified. PLs profile shows an obvious difference among the species, with human milk showing higher SM content and more unsaturated fatty acyls than other mammalian milk. The mammalian milk show a similar core-membrane lipid structure but obvious different size distribution. These data provide a basis for better construction of infant formulas to provide PLs requirements and a similar milk fat globule structure for infants.