New lignans and diterpenoid glycosides from the fruits of Xanthium italicum Moretti. Issue 6 (3rd June 2022)

• Record Type: Journal Article
• Authors: Li, Yu-Tong; Fu, Jiang; Wang, Hai-Qiang; Li, Yong; Liu, Yun-Bao; Ma, Shuang-Gang; Qu, Jing; Yu, Shi-Shan
• Is Part Of: Journal of Asian natural products research. Volume 24:Issue 6(2022)
• Page Start: 518
• Page End: 527
• Publication Date: 2022-06-03
• Subjects: Compositae -- Xanthium italicum -- lignans -- diterpenoid glycosides -- phenolic compound -- antinociceptive activity; Materia medica -- Asia -- Periodicals; Pharmacognosy -- Asia -- Periodicals; Medicinal plants -- Asia -- Periodicals; Medicine, Oriental -- Asia -- Periodicals; 615.321095
• DOI: 10.1080/10286020.2021.1938557
• Languages: English
• ISSNs: 1028-6020

Abstract

Abstract: A pair of new lignans [(+)- 1 and (-)- 1 ] and three new compounds (2-4 ), together with a known compound 5, were isolated from the fruits of Xanthium italicum Moretti. The structures of these compounds were determined on the basis of spectroscopic analysis, particularly HR-ESI-MS and 1 D and 2 D NMR. Compounds 2 and 3 showed antinociceptive effects in an acetic acid-induced writhing test in mice with the writhe inhibition rates of 80.50% and 67.89% at the dose of 20 mg/kg, respectively. Abstract : UF0001