Acorus calamus-zinc oxide nanoparticle coated cotton fabrics shows antimicrobial and cytotoxic activities against skin cancer cells. (December 2021)

• Record Type: Journal Article
• Authors: Vakayil, Ramsi; Muruganantham, Sankareswaran; Kabeerdass, Nivedhitha; Rajendran, Manikandan; Mahadeo palve, Anil; Ramasamy, Srinivasan; Awad Alahmadi, Tahani; S. Almoallim, Hesham; Manikandan, Velu; Mathanmohun, Maghimaa
• Is Part Of: Process biochemistry. Volume 111:Part 1(2021)
• Page Start: 1
• Page End: 8
• Publication Date: 2021-12
• Subjects: Zinc oxide nanoparticles -- Acorus calamus -- Microbial infection -- Skin cancer; Biochemical engineering -- Periodicals; Biotechnology -- Periodicals; Biochemistry -- periodicals; Biotechnology -- periodicals; Chemical Engineering -- periodicals; Génie biochimique -- Périodiques; Biotechnologie -- Périodiques; Biochemical engineering; Biotechnology; Periodicals; 660.63
• DOI: 10.1016/j.procbio.2021.08.024
• Languages: English
• ISSNs: 1359-5113

Abstract

Graphical abstract: Highlights: Acorus calamus rhizome is a good source of zinc oxide nanoparticles (AC-ZnONPs). The synthesized AC-ZnONPs showed good antimicrobial activity. AC-ZnONPs coated fabrics could be used for wound healing and antimicrobial purposes. Abstract: Microbial infections are a general public health problem worldwide, and their resistance to antibiotics has increased rapidly. The prevention of microbial growth on the surface of cotton fabric is essential to control skin-related infections. In this work, we evaluated A.calamus - zinc oxide nanoparticle (AC-ZnONPs) coated cotton fabrics for antibacterial and cytotoxic activities. The formulated AC-ZnONPs were characterized by UV-spectrophotometer, SEM, EDX, FT-IR, and TEM studies. The AC-ZnONPs amalgamation into the cotton fabrics was done by the dipping technique. The antimicrobial activity and cytotoxic activity were executed by standard approaches. The results of UV-spectrophotometer, TEM, and SEM, and EDX proved the formation and existence of AC-ZnONPs on the fabrics' surface. FT-IR results demonstrated the existence of numerous functional groups. AC-ZnONPs efficiently suppressed the growth of the pathogenic microbes with a maximum inhibition at 60 μg of AC-ZnONPs against E.coli and S.aureus . The AC-ZnONPs coated fabrics also prevented microbial growth with maximum inhibition against P.aeruginosa, K.oxytoca, and A.baumanii . In addition, AC-ZnONPs efficiently suppressed the viability of SK-MEL-3 cells. Altogether, our findings disclosed that the AC-ZnONPs coated fabrics displayed excellent antimicrobial activity against the pathogenic microbes and could be utilized in the medical fields in the future.